Infection and inflammation of the male reproductive tract, including the testis, are important causes of male infertility, as they lead to disruption of spermatogenesis and alteration of sperm number and quality1,2. Experimental autoimmune epididymo-orchitis (EAEO) is an established rodent model of ...
although executed by enzymes other than tryptase. Accordingly, if this controlling mechanism is absent, as in tryptase-deficient MCs, aging cells may become more vulnerable to cellular stress as shown here for MCs. However, the validity of this hypothesis on a more general level remains to be ...