Among the transcripts for expected MC-specific proteins such as tryptase, major basic protein (MBP), which had been thought to be eosinophil specific, was ranked fourth in terms of amounts of increased MC-specific messenger RNA. Mature eosinophils were almost lacking this transcript. MCs obtained...
Both nasal symptoms (p≤0.05) and lavage fluid levels of tryptase (p≤0.05), albumin (p≤0.05), and α2-macroglobulin (p≤0.01) were reduced by pretreatment with topical terbutaline sulfate. We conclude that high doses of topical terbutaline may produce significant antiallergic effects in ...
Viral antigen in rgHPAIV infected tissues.Influenzavirus Anucleoprotein antigen (brown) detected by immunohistochemistry in various tissues. Vascular endothelium of capillaries and larger blood vessels is the dominant cell type supporting viral antigen in all tissues (arrowheads). (A) Brain, showing ant...
Mast Cell Tryptase Levels in Gut Mucosa in Patients with Gastrointestinal Symptoms Caused by Food Allergy Background and Aims: Mast cells, which are important effector cells in food allergy, require a special histologic treatment for quantification in endoscopi... A.F.,Hagel,T.,... - 《Interna...
However, transcriptomic features of TMEM173 in B-cell acute lymphoblastic leukemia (B-ALL) remain elusive. Methods: Quantitative real-time PCR (qRT-PCR) and western blotting (WB) were applied to determine the mRNA and protein levels of TMEM173 in peripheral blood mononuclear cells (PBMCs). ...
Levels of NGF-尾 and NT-4 correlated with tryptase levels, suggesting a link between MC load and blood levels of NGF and NT-4. Migration of CD117+ progenitor cells from the blood was enhanced toward NGF-尾 gradient in both mastocytosis and controls. Together with enhanced NT levels, the ...
As other typical markers of mast cell activation, such as tryptase and leukotriene E4, are also elevated in AERD at the baseline, it is generally assumed that most of the PGD2 synthesised in these patients should originate from the same cell source [54]. The mechanism responsible for ...
Introduction Angiogenesis is the formation of new capillary blood vessels from existing blood vessels, and is distinct from the normal vasculogenesis of blood vessels' formation from precursor cells [1]. Apart from its role in pathologies, angiogenesis is a vitally important process in normal growth ...