EGR1 Antibody (12-9851-42) in Flow Normal human peripheral blood cells were stimulated with Anti-Human CD3 Functional Grade Purified (Product # 16-0037-81) for 2 hours. Cells were then intracellularly stained with Anti-Human CD4 APC (Product # 17-0047-42) and Rat IgG2a K Isotype Control...
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E-mail: wuchaoyang9@163.com 4These authors contributed equally to this work. Received 12 September 2016; revised 1 December 2016; accepted 20 December 2016 Egr-1/Atg4B axis regulates radioresistance in HCC W-x Peng et al 2 Figure 1. Egr-1 promotes radioresistance in HCC cells. (a) Egr-...
The mRNA levels of EGR1 (C), ADAM10 (D), ICAM-1 (E), and VCAM-1 (F) in lung tissues were determined by qRT-PCR. Blood samples were isolated 6 h after LPS injection, and serum was analyzed by ELISA for TNF-α (G), IL-6 (H), and IL-1β (I) release. Histological ...
SAH results in a typical neuronal apoptosis, concomitant with a transcriptional upregulation of Bim, E2F1 and Egr-1 but a downregulation of Bcl-2. (a) Representative pictures of the brains are shown after surgery. In SAH rat, significant blood clots mainly distribute at the base of Willis cir...
A new 2-aminosteroid induces cellular differentiation and upregulates the expression of MafB and Egr-1 genes respectively in HL-60 and K562 leukemia cells[J]. HE Qun, LI Qiong, YUAN Lin bo and HE Jun Research Laboratory of Blood Physiology, Department of Physiology, Xiangya School of ...
EGR1 over-expression in chondrocytes using adenovirus could inhibit COl2A1 expression and enhance MMP9 and MMP13 expression. And silencing EGR1, using RNAi, had the opposite effects. Moreover, EGR1 over-expression accelerated chondrocyte hypertrophy in vitro, and EGR1 knockdown reversed this effect...
The serine protease thrombin catalyzes fibrin clot formation by converting fibrinogen into fibrin. Additionally, thrombin stimulation leads to an activation of stimulus-responsive transcription factors in different cell types, indicating that the gene ex
Under baseline conditions at 8–12 weeks of age, there was no difference in blood pressure or heart rate betweenSrsf1−/−mice and their WT littermates (Supplementary Fig. 3b,c), and the thickness of the media wall in uninjured sham-operated carotid arteries was comparable (Fig. 2c)....