HORMONE receptor positive breast cancerHORMONE therapyBREAST cancer treatmentEPIDERMAL growth factor receptorsMESSENGER RNABackground/Aims: Despite effective therapeutic strategies for treating hormone receptor-positive (HR+) breast cancer, resistance to endocrine therapy that is either de novo or acquired ...
在KRAS野生型结直肠癌患者进展后应用西妥昔单抗(Cetuximab After Progression in KRAS wIld type colorectal cancer-Gruppo Oncologico dell' Italia Meridionale,CAPRI-GOIM)研究中进行了一项扩展性转化研究项目,其目的是通过评估液体活检的作用及其...
S1D). We also examined the PELI1 and EGFR protein levels in breast cancer tissue microarray by IHC, and found a highly positive correlation (Fig. 1C, D). Furthermore, the highest co-expression was also detected in breast cancer cells among five kinds of cancer cell lines, including MDA...
Prognostic value of epidermal growth factor receptor in node-positive breast cancer The prognostic significance of EGFR (epidermal growth factor receptor) was studied in a cohort of 68 node-positive patients with breast cancer, who entered... M Grimaux,S Romain,Y Remvikos,... - 《Breast Cance...
方法：应用免疫组化ＭａｘＶｉｎｓｏｎＴＭ法检测乳腺浸润性导管癌和癌旁正常组织中ＥＧＦＲ蛋白的表达。结果：乳腺浸润性癌中ＥＧＦＲ的阳性表达率为６５．０％，癌旁正常组织中的阳性表达率为２０．０％，组间比较差异具有显著性（犘＜０．０５），阳性表达率与淋巴结转移有关（犘＜０．０１）。结论：ＥＧ...
11. Tamiya A, Tamiya M, Nishihara T, et al. Cerebrospinal Fluid Penetration Rate and Efficacy of Afatinib in Patients with EGFR Mutation-positive Non-small Cell Lung Cancer with Leptomeningeal Carcinomatosis: A Multicenter Prospective Study. Antic...
Methods: TNBC lines (MDA-MB-468, HCC-1395, and MDA-MB-231), and a hormone receptor-positive breast cancer line (T47D) were stimulated with epidermal growth factor (EGF) and hepatocyte growth factor (HGF). Lines were then treated with different concentrations of EGFR inhibitors (gefitinib ...
cancer tissue were 38.2%(26/68),42.6%(29/68),52.9%(36/68) and 60.3%(41/68) corresponding.An obvious increasing tendency as the differentiation of the cancer degraded,invasion depth deepened,lymphatic metastasis occurred and TNM stage upgraded was showed by the positive expression rates of them...
05was considered statistically significant.RESULTS ：The positive rate of EGFR expression in breast invasive ductal carcinoma was 48.7%which was significantly higher than that in invasive lobular carcinoma (24.0%)and fibroadenoma (16.7%)(P <0.01).The positive rate of HER-2expression in breast ...
Bispecific Her2 x cotinine antibody in combination with cotinine-(histidine)2-iodine for the pre-targeting of Her2-positive breast cancer xenografts. J. Cancer Res. Clin. Oncol. 140, 227–233 (2014). CAS PubMed Google Scholar Park, S., Lee, D. H., Park, J. G., Lee, Y. T. & ...