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EGFR突变肺癌靶向耐药后出现BRAF突变,三靶治疗?EGFR(epidermal growth factor receptor, 表皮生长因子受体)突变是非小细胞肺癌(non-small cell lung cancer, NSCLC)中最常见的驱动基因,高达50%以上的东亚患者存在该突变[1]。EGFR抑制剂(EGFR TKI)治疗对EGFR突变的晚期NSCLC患者与化疗相比具有更好的疗效[2]。...