英文名称:EGFR-IN-7 (compound 34) 品牌:MedMol 分子式:C32H41BrN9O2P 货号:S89109-5mg 产地:上海 纯度:98% 是否进口:否 EGFR-IN-7 CAS:2267329-76-8纯度:98%分子式:C32H41BrN9O2P分子量:694.6保存:-20°C外观:品牌:MedMol货号:S89109-5mg产品包装:5mg,10mg,25mg,100mg 上海源叶生物科技有限公司(...
EGFR-IN-7 (compound 34) 是一种有效选择性的 EGFR 激酶抑制剂,对 EGFR (WT) 和 EGFR (mutant C797S/T790M/L858R) 的 IC50 值分别为 7.92 nM 和 0.218 nM,具有抗肿瘤活性,详细信息请参考专利 WO2019015655A1。 EGFR-IN-7 Chemical Structure CAS No. : 2267329-76-8 规格价格是否有货数量 5 mg ￥...
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EGFR/HER2-IN-7 is a highly selective and potent anticancer compound designed to target MCF-7 breast cancer cells by functioning as a dual inhibitor of EGFR/HER2 kinases and DHFR (dihydrofolate reductase), with IC50 values of 0.18 μM for EGFR, 0.146 μM for HER2, and 0.907 μM for DHFR...
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5. http://app1.nmpa.gov.cn/data_nmpa/face3/dir.html?type=yp&CbSlDlH0=qGqxcaqtcGLtcGLtc7AUkdzGX6LJJsOr_5cEWvs_znAqqqL 6. M.G, Kris, and, et al. Objective regressions in non-small cell lung cancer patients treated in Phase I trials of oral ZD1839 (IressaTM), a selective tyrosine...
[7]PLANCHARD D, BESSE B, GROEN H J M, et al. Dabrafenib plus trametinib in patients with previously treated BRAFV600E-mutant metastatic non-small cell lung cancer: an open-label, multicentre phase 2 trial [J]. The Lancet Oncology, 2016, 17(7): 984-93.[8]PLANCHARD D, SMIT E F, ...
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