Basic informationMore Product Name:TIM3 / HAVCR2 / CD366 (Effector T-Cell Marker) Antibody Synonyms:TIM3 / HAVCR2 / CD366 (Effector T-Cell Marker) Antibody CAS: MF: MW:0 EINECS: Mol File:Mol File Browse by Nationality Suppliers>China suppliers
T-cell markerImmunotherapies aimed at enhancing natural or endogenous antitumor T-cell immunity in patients affected by advanced malignancies are currently being implemented in the clinic with promising results. In order to optimize therapeutic protocols and monitor the effectiveness of such therapies, ...
Helper T cell differentiation, inside and out Effector cellspossess a ‘memory’. They reiterate cytokine synthesis upon re-encounter with antigen, which remains a heritable trait of all subsequent progeny[8,10–12]. This can be explained by the stability of epigenetic remodeling, which confers li...
The decrease in HIF-1α (Del) tumor growth was no longer observed when host NK cells were depleted from tumor-bearing mice (Fig.3Aand Supplementary Fig.1C). CD8+T cell depletion also partially rescued the growth inhibition of HIF-1α (Del) tumors but to a lesser extent (Fig.3Band Sup...
Radar plots (c) CD4 and (f) CD8 demonstrate the mean T cell response for each vaccination group according to cytokine expression levels as a marker of function. Full size image A similar trend was observed for CD8 + responses with greater number of responders in the TC0.4 + IM...
Viability of EM CD8+ T cells (right panel). (E) Surface marker expression on activated naive CD8+ T cells after 24 h. Pooled data from n = 4 independent experiments (left panel). Abundance of inflammatory cytokines in corresponding cell culture supernatants. The dashed line indicates ...
t ion of a novel pancreatic islet autoan ti— gen—specifi c CD 4 T reg th at exp ressed h igh levels of cell surface marker CD 52 . Soluble CD 52 was also used by the cell as an effector molecul e for suppression. T herefore,th e CD 5 2 molecul e is both a surf...
(dendritic cell,DC)表型及体内靶向沉默Gata3 表达 对妊娠期哮喘病变局部免疫与炎症应答改变的影 响,阐明 CD4 + T 细胞及其亚群分化的确切机制,为 控制疾病进程与免疫干预治疗提供靶点。 1 材料与方法 1. 1 材料 SPF 级雌性 BALB/ c 小鼠24 只,6 ~ 8 周龄,体 重18 ~ 20g / 只( 第四军医大学实验动...
contains at least 162 candidate RxLR effectors discovered in our recent studies, but their roles in infection and pathogenicity remain to be determined. Here, we characterize in depth one of the putative RxLR effectors, PvRxLR16, which has been reported to induce cell death inNicotiana benthamiana...
In humans, CD3+CD4+ non-Treg cells can upregulate FOXP3 and associated markers that as such can serve as markers for T cell activation3. We indeed observed a slight upregulation of FOXP3, CTLA4, and TIGIT at mRNA and protein level in SF non-Treg cells but not near the levels observed...