REVIEWS EFFECTOR AND MEMORY T-CELL DIFFERENTIATION: IMPLICATIONS FOR VACCINE DEVELOPMENT Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, Georgia 30322, USA. Correspondence to R.A. e-mail: ra@microbio. emory.edu DOI...
Activated effector and memory T cells contribute to circulating sCD30: potential marker for islet allograft rejection. Am. J. Transplant. 8, 1798-1808.Saini, D.; Ramachandran, S.; Nataraju, A.; Benshoff, N.; Liu, W.; Desai, N.; Chapman, W.; Mohanakumar, T. Acti- vated effector ...
ARTICLES Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin Andrew M Intlekofer1, Naofumi Takemoto1, E John Wherry4,8, Sarah A Longworth1, John T Northrup1, Vikram R Palanivel1, Alan C Mullen1, Christopher R Gasink1, Susan M Kaech4,8, Joseph D Miller4, ...
Asthma is associated with chronic airway inflammation, suggesting that its pathogenesis is driven by type 2 helper T (Th2) cells among memory/effector CD4^+ T, cells. CCR4, a chemokine receptor, is considered a preferential marker for Th2 cells. Another chemokine receptor, CCR7, is regarded ...
Here, using magnetic beads and fluorescence-activated cell sorting, we extensively phenotype the Tck effector cells and conclude that effector function resides within the CD4+CD45RO+, CCR7-, CD49dhigh population, and that these cells are derived from the effector memory CD4+ T cells in resting...
Human Vγ9/Vδ2 effector memory T cells express the killer cell lectin-like receptor G1 (KLRG1) The killer cell lectin-like receptor G1 (KLRG1) is expressed in natural killer (NK) cells and effector memory alphabeta T cells. Gammadelta T cells represe... Matthias Eberl,Rosel Engel,Silk...
Glycosylation changes on surface molecules of T cells affect cell trafcking and function and may be useful in discriminating between naive, effector, and memory T cells. To analyze oligosaccharide structures on T cells activated in vivo, we examined alterations in sialic acid residues on T cells ...
CD27hi populations (whether CD43hi or CD43lo) contained CD62Lhi and CD62lo subsets and displayed markers of typical memory CD8+ T cells, including high expression of the cytokine receptor chains CD122 and CD127, with low expression of the “effector cell” marker, KLRG1 (Figure 1C). ...
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Regulatory CD25(+)CD4+ T cells (Treg cells) are a central element of peripheral tolerance. Little is known, however, about phenotypic and functional charac... Markus,Kleinewietfeld,Fabiola,.....
The dominant subset of circulating human γδ T cells, i.e., Vγ9/Vδ2 cells, constitutively expresses serine esterases and the ‘memory markerˈ CD45RO, which has been taken as evidence of their activated status in vivo [56], [58]. In agreement with a more activated state, γδ ...