alternative (alt) allele是effect allele reference (ref) allele是other allele
major allele 与 minor allele 通常针对某一大小确定的特定群体而言,频率最高的allele为该群体的major allele, 频率次高的为 minor allele,对于最常见的bi-allelic SNP来说,两个allele频率一高一低,就是这个群体中这个snp的major和minor allele,对于tri- 或者quad-allelic SNP (位点有三种或四种碱基的SNP)而言,mino...
1.SNP ID :通常是rs开头,但是如果遇到不是的时候,我们可以通过查询网络看看可不可以互换 2.Effect allele(alternative allele):效应位点 3.Other allele(reference allele):其它位点 4.Beta(OR):如果是连续型变量就是Beta,如果是二分类变量就是OR,代表突变究竟有益还是有害 5.Standard error:置信区间 6.Pvalue ...
We suggested that the first intron structural changes in the VRN-B1c allele as compared with VRN-B1a result in a higher level of VRN-B1 transcripts and an earlier heading time. We confirmed that the expression of the dominant VRN-1 gene induces transcription of the recessive homoeoalleles, ...
Other human polymorphisms, such as the CCR2 64I and the CCR5 promoter -2459 A/G transition that has been discovered recently, have also been shown to influence HIV progression. Since genetic linkages make these polymorphisms interdependent variables, the aim of the present study was to isolate ...
SNVs are not really “mutations,” because by definition they are relatively common in a population (most definitions of a polymorphism indicate that the variant allele should be present at a frequency of 1% or more in a population). However, common SNVs did arise through a germinal mutation...
Genetic marker effects and type of inheritance are estimated with poor precision when minor marker allele frequencies are low. A stable composite populatio... RG Tait,SD Shackelford,TL Wheeler,... - 《Journal of Animal Science》 被引量: 0发表: 2018年 Genetic associations between carcass traits ...
Inheritance of the apolipoprotein E (apoE) 4 allele increases the risk for Alzheimer's disease and may also influence the pathogenesis of other neurodegene... WA Pedersen,SL Chan,MP Mattson - 《Journal of Neurochemistry》 被引量: 252发表: 2010年 Apolipoprotein E polymorphism in the Netherlands ...
There were no significant differences in the area covered by Alz-50 or in the proportion of Alz-50-stained neurons in the nucleus basalis of Meynert of Alzheimer's disease (AD) patients with one or two ApoE epsilon4 alleles as compared with those without any ApoE e4 allele. However, ...
supersedurefrequencybreedingSummaryThe effect of supersedure breeding programmes (replacing each queen with her own daughter) on the maintenance of allelic diversity at the sex-determining locus of the honeybee (Apis mellifera) is analysed. In the models considered, the variances of the allele ...