Recent advances in base editing have created an exciting opportunity to precisely correct disease-causing mutations. However, the large size of base editors and their inherited off-target activities pose challenges for in vivo base editing. Moreover, the
and are randomly assigned in most of the chromosomes of the orthologous species (Fig.5). To determine the evolutionary status of the putativeLusHSFgene paralogues and orthologues, the ratio of substitution rates of non-synonymous (dN) versus synonymous (dS) sites was computed for each pair of ...
In this section, as a preliminary validation, we verify the accuracy of the proposed model that predicts post scores representing engagement rates on social media from the image and text. Section 4.1 and Section 4.2 provide validation settings and results, respectively. 4.1. Validation Settings In ...