Recent advances in base editing have created an exciting opportunity to precisely correct disease-causing mutations. However, the large size of base editors and their inherited off-target activities pose challenges for in vivo base editing. Moreover, the
leading to genome modifications during the repair process3. However, it is still challenging to create mutations in some transformation-recalcitrant species, such as wheat, soybean, sorghum, cotton and woody plants. Moreover, the introduced CRISPR/Cas9 DNA usually becomes integrated into plant chromoso...
Melchinger AE, Winter M, Mi X, et al. Controlling misclassification rates in identification of haploid seeds from induction crosses in maize with high-oil inducers. Crop Sci. 2015;55(3):1076–1086. (Open in a new window)Web of Science ®(Open in a new window)Google Scholar ...
the ratio of substitution rates of non-synonymous (dN) versus synonymous (dS) sites was computed for each pair of duplicated genes. The dN/dSratios computed for all the putative paralogues and orthologues
The values of Accuracy and F-measure seem low for the classification task, but comparable values have been shown in a similar study [19]. Table 2. Accuracy and F-measure of the proposed and comparative models in predicting classes for engagement rates. Bold values indicate the best results. ...