In addition to dystrophin, β-dystroglycan has also been shown to bind to the adapter protein, growth-factor-receptor-bound protein 2 (Grb2, not shown)d. This interaction might have a role in extracellular-mediated signal transduction, suggesting that the role of the DPC in muscle is not ...
1989. A second gene of the dystrophin family encoding utrophin (dystrophin-related protein 1) is also expressed in Schwann cells Love et al. 1989, Matsumura et al. 1993. Recently, a third member of the dystrophin family, dystrophin-related protein 2 (DRP2), has been identified, the ...
dystrophin-related protein 2 (RACE): rapid amplification of cDNA ends (DAH): discontinuous actin hexagon (DGC): dystrophin-glycoprotein complex (RNA): ribonucleic acid (DNA): deoxyribonucleic acid (Y2H): yeast two-hybrid (EGFP): enhanced green fluorescnet protein (ER): endoplasmic re...
Dystrophin-related protein (DRP) is an autosomal gene product with high homology to dystrophin. We have used highly specific antibodies to the unique C-terminal peptide sequences of DRP and dystrophin to examine the subcellular localization and biochemical properties of DRP in adult skeletal muscle....
dystrophin-related protein 2 (DRP2)Dystrophin-related protein2(DRP2) 3)dystrophindystrophin蛋白 1.Dystrophinopathies are X-linked recessive diseases caused by the complex mutations of the giganticdystrophingene(DMD).DMD基因庞大,突变机制复杂,随着分子生物学的进展,对DMD基因及其所编码dystrophin蛋白的认识不...
According to the "frame-shift hypothesis" DMD muscle should not synthesize any dystrophin through to the C-terminus and it has been suggested that the protein detected is not dystrophin, but a related autosomal homologue. We have labelled serial sections of DMD muscle with specific monoclonal ...
dystrophin-related protein structure CAS No. Chemical Name: dystrophin-related protein Synonyms dystrophin-related protein CBNumber: CB81353756 Molecular Formula: Molecular Weight: 0 MDL Number: MOL File: Mol file Request For Quotation...
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Chromosome 6-encoded dystrophin-related-protein (DRP) shows significant structural similarities to dystrophin at the carboxyl terminus, though the two proteins are encoded on different chromosomes. Both DRP and dystrophin are expressed in muscle and brain and show some similarity in their subcellular loc...
Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle. Neuron. 1991; 7 :499–508.Ohlendieck K, Ervasti JM, Matsumur K, Kahl SD, Leveille CJ, Campbell KP: Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle. Neuron 1991...