Here we report that in humans and rodents, subsets of neurons in the mediobasal aspect of the ARC are enmeshed in PNN-like structures. In mice, these neurons are densely packed into a continuous ring that encircles the junction of the ARC and median eminence, which facilitates exposure of ...
only offering relief from the symptoms rather than focusing on the vital cause of the disorder. The exact pathogenesis of these diseases influenced by RONS is still not fully understood despite extensive research. Several cellular enzymes continulsy neutralizes these RONS produced in the cells, but ...
In the industrial field, the pn-junction in solar cells, where the photoinduced electron transfer occurs, is the fundamental building block of semiconductor devices. The reverse process is also used for light-emitting diodes5. In synthesis, photocatalytic reactions initiated by the absorption of ...
It is generally considered that cleavage of the PV VP0 into VP2 and VP4 occurs as a result of the formation of complete virus particles and may include involvement of the viral RNA (Basavappa et al., 1994; Hindiyeh et al., 1999). However, for FMDV, it appears that cleavage of VP0...
Microglia regulate the response to injury and disease in the brain and spinal cord. In white matter diseases microglia may cause demyelination. However, how microglia respond and regulate demyelination is not fully understood. To understand how microglia
The hallmarks of neurons are their slender axons which represent the longest cellular processes of animals and which act as the cables that electrically wire the brain, and the brain to the body. Axons extend along reproducible paths during development a
during the final stages of cytokinesis. Surprisingly, we observe that egress from the host cell is not an actin-dependent process. Finally, we show that parasites lacking PfACT1 are capable of microneme secretion, attachment and formation of a junction with the erythrocyte, but are incapable of...
of germ cells for the entire reproductive life of the female. They remain dormant until their recruitment and irreversible growth towards the primary, secondary and tertiary stages (with an antral cavity). The gradual exit of primordial follicles begins shortly after the formation of the primordial ...
(NP) disorders. Astrocytes proliferate, differentiate and mature during the critical period of early postnatal brain development, a time window of elevated glia-dependent regulation of a proper balance between synapse formation/elimination, which is pivotal in refining synaptic connectivity. Therefore, ...
This effect, potentially linked to the ssDNA/dsDNA junction’s conformation, might play a role in regulating binding preference enabling high processivity amidst rapid protein exchange. Taken together, our findings support an autonomous replication model that includes rapid protein exchange, burst of ...