Advise patients of the risk of bleeding associated with concomitant use of duloxetine with aspirin or other nonsteroidal anti-inflammatory agents, warfarin, or other drugs that affect coagulation. Inform patients of other important precautionary information.Additional...
Check with your doctor before taking any CNS depressants while you are taking this medicine. Aripiprazole may cause drowsiness, trouble with thinking, or trouble with controlling movements, which may lead to falls, fractures or other injuries. Do not drive or do anything else that could be ...
Since these drugs act to suppress the pathological neuronal hyperexcitability that constitutes the final substrate in many seizure disorders, it is not surprising that they are prone to causing adverse reactions that affect the CNS.Information on adverse effects of the older AEDs has been mainly ...
Drugs & their effects on the CNS
Major depressive disorder (MDD) is a common disease defined by sadness and a loss of interest or pleasure in activities. Depression treatments include therapy and antidepressant medication. Most available antidepressants affect the same types of chemicals that communicate in the brain (neurotransmitters)...
Izumi T, Inoue T, Kitagawa N, et al. Open pergolide treatment of tricyclic and heterocyclic antidepressant-resistant depression. J Affect Disord 2000; 61: 127–32 ArticlePubMedCASGoogle Scholar Lattanzi L, Dell’Osso L, Cassano P, et al. Pramipexole in treatment-resistant depression: a 16-wee...
In the CIS countries asthma is diagnosed in 10% of children. Most often, the disease is diagnosed in a child aged 2-5 years. But, as medical practice shows, an illneβ can affect a child of any age. It should be noted that bronchial asthma is not completely treated. In some cases,...
they affect the number of drugs that may be registered by regulatory authorities, the time to discover and develop drugs, and the cost of drug ... I Kola - 《Clinical Pharmacology & Therapeutics》 被引量: 290发表: 2008年 Overview of different pharmacotherapies for attaining remission in gener...
KarXT (xanomeline-trospium), comprised of muscarinic agonist xanomeline and muscarinic antagonist trospium, is designed to preferentially activate muscarinic receptor in the CNS and ameliorate the peripheral muscarinic side effects. It is reported that KarXT improves cognition in patients with AD and sc...
That is, these variants are highly likely to tangibly affect the behavior of certain gene expressions, most often nearby genes. We find four variants with a conserved class prediction greater than 95%, and three of these variants also possess a regulatory prediction greater than 95%. That is,...