Drugs Acting on CNS: Se- lected Topics in Experimental Pharmacology [M]. Mohanlal B. Kothari Book Depot, 1972.Seth UK, Dadkar NK, Kamt UG. Bombay: Mohanlal B. Kothari Book Depot; 1972. Drugs acting on CNS: Selected topics in experimental pharmacology....
Geriatric Patients, or in the presence of debilitating disease.2 mg to 2.5 mg, 1 or 2 times daily initially; increase gradually as needed and tolerated PEDIATRIC PATIENTS: Because of varied responses to CNS-acting drugs, initiate therapy with lowest dose and increase as required. Not for use ...
If alternate-day therapy is preferred, only use a “short-acting” glucocorticoid that suppresses the HPA axis <1.5 days after a single oral dose (e.g., prednisone, prednisolone, methylprednisolone). Some conditions (e.g., rheumatoid arthritis, ulcerative colitis) require daily glucocorticoid thera...
Therapeutic agents acting on the renin–angiotensin system (RAS) might be able to modulate the concentration of ACE-2 and the various components of the system. Here, we discuss current pharmacological, molecular, and clinical evidence to investigate whether drugs acting on RAS with modulation of ...
examplesofultrashortandintermediateactingbarbituratesandtheirrespective durationofactionaremeasured.AdministeringsimultaneouslyanotherCNS depressant,ethylalcohol,canmodifythedurationofactionofpentobarbitone. Thesecondpartofthispracticalwilldemonstratepharmacologicaldrugantagonism. ...
GABA has been for many years, and continues to be, a major target for research into the design and development of newer antiseizure medications. Cenobamate and ganaxolone are the latest antiseizure medications acting on GABA that have entered the market. ...
To date, robust evidence on the role of propofol based on large, randomized, controlled trials for this serious condition is still lacking [136]. 4.3 Thiopental, Pentobarbital Thiopental sodium and pentobarbital are barbiturates acting as GABA-A agonists, with enhanced inhibitory neurotransmission and...
摘要: Summary This chapter contains sections titled: Introduction Antipsychotic Drugs Antidepressant Drugs Drugs for Epilepsy and Bipolar Disorder Anxiolytic Drugs Centrally Acting Analgesic Drugs Drugs for treating Substance Abuse and ADHD Drugs for Neurodegenerative Diseases Future Prospects for New CNS Drugs...
We have recently studied several natural product constituents which have effects on the CNS. (1) Tetrahydropalmatine (THP) and its analogues were isolated from Corydalis ambigua and various species of Stephania. (+)-THP and (-)-THP possess not only analgesic activity, but also exert sedative-tra...
Induction of emesis generally should not be attempted, since a phenothiazine-induced dystonic reaction of the head or neck may result in aspiration of vomitus during emesis; centrally acting emetics are of little value in the management of promethazine overdosage. Administration of a saline cathartic...