including a single origin of all CQR alleles in Southeast Asia and Africa, two independent origins in South America, one in Papua New Guinea, and at least one origin in Melanesia
1493TheuseoftobaccoisintroducedintoEuropebyColumbusandhiscrewreturningfromAmerica.1691InLuxembourg,Germany,thepenaltyforsmoking(tobacco)isdeath.1800Napoleon'sarmy,returningfromEgypt,introducesmarijuanaintoFrance.1839-42ThefirstOpiumWar.TheBritishforceuponChinathetradeinopium,atradetheChinesehaddeclaredillegal.1856The...
听力原文: The Tokyo stock market responded calmly yesterday to the collapse of two Japanese financial institutions, with prices finishing higher on strength in high-tech issues. The US dollar fell back against the Japanese yen. The dollar started higher in Tokyo amid concern about the collapse of...
Monitoring adverse drug events or pharmacovigilance has been promoted by the World Health Organization to assure the safety of medicines through a timely and reliable information exchange regarding drug safety issues. We aim to discuss the application of machine learning methods as well as causal infere...
Like some other generics players, quality issues have affected Sun recently. In October, the companyrecalledmore than 100,000 bottles of tadalafil, a generic of Eli Lilly's Cialis. An “incorrect grade” of inactive ingredient that was added during production triggered the recall, according to th...
Despite the existence of an effective vaccine, annual measles deaths worldwide have remained constant at around 150,000 since 2007. The reasons for this are the highly infectious nature of the virus, in the developing world largely due to issues of resources, and in many developed countries in...
With the extensive role of microbes in human health, they have an enormous potential to be used as therapeutics for disease management and acts as the potential source to achieve the objective of personalized therapy by overcoming key issues like interpersonal variability and stability in every type...
Traditional medicine has a long history of clinical practice in many countries due to the fact that nature provides a rich source of active ingredients for multi-target therapies. Natural products are also more affordable to most patients, along with the convenience of self-medication. However, con...
Most strains isolated in Europe and North America fall into one of three genotypes, referred to as types I, II and III. Type I are considered the most virulent strains and are lethal in mice, displaying enhanced migratory capacity both in vitro and in vivo, the faster growth rate being in...
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