Fellows Column: Drug Shortages in the USA is a Persistent ProblemRamakrishnan, AkshayaRamachandran, VarshaNeonatology Today
The renal Fanconi syndrome which results from renal tubular dysfunction can be either associated with various inbom errors of metabolism or acquired from various etiology. We report a case of gentamycin-induced Fanconi syndrome in a 4-month old infant who presented with aminoaciduria, glucosuria, ...
G. E. The challenging problem of disease staging in human African trypanosomiasis (sleeping sickness): a new approach to a circular question. Trans. R. Soc. Trop. Med. Hyg. 111, 199–203 (2017). Article PubMed Google Scholar Steinmann, P., Stone, C. M., Sutherland, C. S., ...
Drug toxicity is a key problem in pharmacology and is one of the main reasons for the high cost of drug development. While many studies characterize drug effects using just one or two methodological approaches, there is always a risk to form incorrect conclusions. It is important to keep in ...
Community Reactions to Campaigns Addressing Crystal Methamphetamine Use Among Gay and Bisexual Men in New York City Crystal methamphetamine (aka "crystal meth") use with high-risk sex has become an emerging health problem for gay and bisexual men in New York City since t......
Stable crystal forms of drugs pose problem in solubilization due to high lattice energy. Thus, disordered amorphous forms offer distinct advantage over crystal forms with regards to solubility. Hence, changing the solid state characteristics of active pharmaceutical ingredient (API) renders the molecule ...
DCB delivery. Furthermore, the presence of calcium in a plaque acts as an impenetrable structural diffusion barrier that prevents tissue from being accessed. To overcome this problem, a study on intraluminal PTX delivery to human peripheral arteries with significant calcified plaque estimates that ...
I am a shift supervisor for a retail drug store chain. Like a lot of retailers, we are having a very bad shoplifting problem. Thieves will come, fill bags with hundreds, if not thousands of dollars of merchandise, and walk out. (We are well aware that these are a part of much larger...
Since the introduction of insulin almost a century ago, more than 80 peptide drugs have reached the market for a wide range of diseases, including diabetes, cancer, osteoporosis, multiple sclerosis, HIV infection and chronic pain. In this Perspective, we
environment60, which would already suggest a problem of a different magnitude—that the antibiotic concentrations in the environment are literally sterilizing the environment, which seems unlikely61. We suggest that the insertion of introns into transgenes to break their coding sequences could be both...