Drug-Drug Interaction In subject area:Pharmacology, Toxicology and Pharmaceutical Science A drug-drug interaction is a phenomenon in which the effects of a drug are altered by the presence of another drug or drugs. From:Forensic Toxicology (Second Edition),2022...
This chapter focuses on aspects of pharmacology, those of drug interactions. The context is that of use by patients of one or more drugs for preventive, diagnostic, or therapeutic purposes. When taking more than one drug at a time, a patient may experience effects that can be ascribed to ...
Crooks, J. and Moir, D. C.(1974) The detection of drug interaction in a hospital environment, inClinical Effects of Interaction between Drugs(eds L. E. Cluff and J. C. Pétrie) Excerpta Medica, Amsterdam, pp. 255–62. Google Scholar Das, U. N.(1982) Modification of anti-hypertensive...
Drug Interaction Facts, Drug-Reax, Lexi-Interact, Pharmavista, Stockley’s Drug Interactions, The Medical Letter and Vidal ,常用于处方 (用 药医嘱)的检查,以发现最具临床相关性的DDI Drug-Reax (Micromedex®) Lexi-Interact Pharmavista 信息系统识别DDI 此外,一些其它的数据库也列出了已知的DDI,包括:Da...
Some drugs influence the gastro-intestinal absorption, distribution, metabolism or renal excretion of other drugs, i.e. processes involved in pharmacokinetic interactions. The clinical consequences of pharmacokinetic drug-drug interaction will be either an increase or a decrease in known therapeutic or to...
Editorial: Drug-drug interactions in pharmacology In pharmacology, drug-drug interactions result in unintended reactions, toxic side effects, or a lack of clinical efficacy in an individual body when multi... S Pichini,AD Trana,García-Algar,... - 《Frontiers in Pharmacology》 被引量: 0发表:...
Drug鈥揹rug interaction (DDI) can result when one drug alters the pharmacokinetics of another drug or its metabolites. The assessment of pharmacokinetic DDIs during clinical development is a part of the general clinical pharmacology and ... P Stopfer - Drug Discovery and Evaluation: Methods in ...
By usingin vitropreparations of human enzymes it is increasingly possible to predict those antibiotics that will adversely affect the metabolism of other drugs. In addition, between-patient variability in frequency of interaction may relate to differences in the activities of these enzymes. Although the...
Drug interaction and chronic obstructive respiratory disorders Paola Rogliani, Beatrice Ludovica Ritondo, Bartolomeo Zerillo, Maria Gabriella Matera, Luigino Calzetta Article 100009 View PDF select article Drug-drug interactions in polypharmacy patients: The impact of renal impairment ...
However, although some interactions may be life threatening, many are only theoretical or clinically trivial. Nevertheless it is always wise to check interactions in an appropriate reference work. 展开 关键词: pharmacology drug interaction dietary supplements herbal medicines pharmacokinetics pharmacodynamics ...