英文名称:Dynamin-1-Like Protein (DRP1) Antibody,中文名称:动态蛋白-1样蛋白(DRP1)抗体,产品货号:Catalogue No: abx010669,Dynamin-1(Dyn1)属于Dynamin家族,含有864个氨基酸蛋白(约95kDa)。Dynamin-1(神经元特异性)、Dynamin-2(广泛表达)和D
H., Hocart, C. H., Arioli, T., & Williamson, R. E. (2007). Arabidopsis dynamin-like protein DRP1A: a null mutant with widespread defects in endocytosis, cellulose synthesis, cytokinesis, and cell expansion. Journal of Experimental Botany, 59(2), 361-376. doi:10.1093/jxb/erm324...
In vitro and mouse studies suggest that decreasing DRP1 activity could help treat HD. In human neurons expressing a mutant form of the huntingtin (HTT) protein, expression of a DRP1 variant with less enzymatic activity led to lower mitochondrial fragmentation and less cell death than expression of...
Overall, our results implicated that Shh signaling modulates antioxidant defense system and stabilizes mitochondrial dynamics by suppressing Drp1 protein which maintains the survival of EH cells against oxidative stress. 展开 关键词: Dynamin-like GTPase Drp1 Endometrial hyperplasia Estrogen Mitochondrial ...
Findings: The results showed that eight weeks of HIIT caused a significant increase in DRP1 in the hearts of old rats, while it did not significantly change the content of OPA1 protein. Conclusion: HIIT protocol seems to improve mitochondrial quality control in the heart of aged rats.Marezloo...
Rh1 incubation also reversed the changes in both protein and mRNA expressions of 伪-SMA, vimentin, and osteopontin induced by Ang II. Besides, Ang II enhanced protein expression and promoter activity of KLF4, a key regulator of phenotypic switching, whereas pretreatment with Rh1 reversed these ...
Protein Structure, TertiaryMutationMolecular StructureAmino Acid SequenceMolecular Sequence DataMammalian Drp1 is a dynamin-like GTPase required for mitochondrial fission. Although it exists primarily as a cytosolic homo-tetramer in vivo, it can also self-assemble into higher order structures on the ...
Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo Neuronal cell death in a number of neurological disorders is associated with aberrant mitochondrial dynamics and mitochondrial degeneration. However, the t......
Dynamin1-like protein (DNM1L; P < 0.01), the gene that codes for Drp1, and Optic atrophy 1 (OPA1; P = 0.05) were significantly upregulated ... Ciaran,E,Fealy,... - 《Journal of Applied Physiology》 被引量: 48发表: 2014年 ...