Protein Name: Dynamin-1-like protein Human Gene Id: 10059 Swiss-Prot: O00429 Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Source: Polyclonal, Rabbit Dilution: WB: 1:500-1:2000 IHC-p: 1:100-300 ELISA: 1:20000 IF: 1:100-300 Purification: Th...
Cat No.26187-1-AP 浓度:500 ug/ml 库存:现货 点击咨询售前客服 点击咨询售后客服 Mol Cell An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation humanWB EMBO Mol Med High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fi...
Interfering with interaction between TBC1D15 and Drp1 abrogated asymmetrical mitochondrial fission and mitochondrial function. Cardiac phenotypes of TBC1D15CKO mice upon I/R injury were rescued by adenovirus-mediated overexpression of wild-type but not mutants (R400K, ∆231–240 and ∆574–624)...
(b) YFP-Drp1 ∆15 shows reduced interaction with Mff in HEK293 cells. GFP-TRAP samples and lysates from cells expressing YFP, YFP-Drp1 or YFP-Drp1 ∆15 were immunoblotted with Mff, GFP, and β-actin antibodies. (c) Decreased mitochondrial association of YFP-Drp1 ∆15. YFP-Drp1R ...
The binding of MiD49 to Drp1 is regulated by GTP-dependent oligomeric changes of Drp1. In ischemia and hypoxia, the interaction between MiD49 and Drp1 is a “binding into a loop and then dissociating” process. Drp1 has several binding sites for MiD49. The GTPase domain of Drp1 can bind...
Dynamin-1-like protein (Dnm1L) interaction with kinesin light chain 1 (KLC1) through the tetratricopeptide repeat (TPR) domains. Biosci, Biotechnol, Biochem. 2014;78:2069–72. CAS Google Scholar Glater EE, Megeath LJ, Stowers RS, Schwarz TL. Axonal transport of mitochondria requires ...
Recruited to the mitochondrial outer membrane by interaction with MIEF1. Colocalized with MARCH5 at mitochondrial membrane. Localizes to mitochondria at sites of division. Localizes to mitochondria following necrosis induction. Associated with peroxisomal membranes, partly recruited there by PEX11B. May ...
In ischemia and hypoxia, the interaction between MiD49 and Drp1 is a "binding into a loop and then dissociating" process. Drp1 has several binding sites for MiD49. The GTPase domain of Drp1 can bind to the dynamic-related region (DRR) domain of MiD49, which is vital for the gradual ...
partly recruited there by PEX11B. May also be associated with endoplasmic reticulum tubules and cytoplasmic vesicles and found to be perinuclear. In some cell types, localizes to the Golgi complex (By similarity). Recruited to the mitochondrial outer membrane by interaction with MIEF1. Binds to ...
The mechanism of interaction of Kupffer cells with Drp1 and NLRP3 to aggravate IRI has not been clarified. Methods A mouse model of hepatic steatosis was established by feeding the mice with a high-fat diet. In vitro experiments were performed using AML12 normal mouse liver cells and RAW264.7...