Studies regarding the association between dietary fat intake and gestational diabetes mellitus (GDM) are limited and provide conflicting findings. Thus, th
Does dietary maternal micronutrient restriction alters offsprings fat metabolism and mtDNA damage and predispose the offspring to insulin resistance and hypertension in later life?J.V.L., KavithaJ.A., Jerald
Use of model organisms and in vitro techniques relevant to developmental biology and medicine are acceptable, as are translational human studies.doi:10.1203/00006450-198909000-00030McClean, PSagher, F AAkhtar, TDodge, J APediatric Research
There is a difference of opinion about whether the percentage of dietary fat plays an important role in the rising prevalence of overweight and in its treatment once it has developed. We believe that ample research from animal and clinical studies, from controlled trials, and from epidemiologic an...
Insulin resistance is when the cells in your muscles, fat, and liver become less sensitive to insulin hormone which means they can’t easily take up and or utilize the glucose from your blood. In this scenario, the pancreas responds by secreting more insulin to help channel the excess glucose...
Reducing total dietary fat without reducing saturated fatty acids does not significantly lower total plasma cholesterol concentrations in normal males. Reducing total dietary fat without reducing saturated fatty acids does not significantly lower total plasma cholesterol concentrations in normal males. Am J ...
Hill JO, Fried SK, DiGirolamo M: Effects of a high-fat diet on energy intake and expenditure in rats. Life Sci 1983,33(2):141-149. Article CAS Google Scholar Harrold JA, Widdowson PS, Clapham JC, Williams G: Individual severity of dietary obesity in unselected Wistar rats: relationship...
3, 4 However, an LCHFD does not necessarily result in weight reduction, and high dietary fat in animal studies, regardless of effects on body weight, has been shown to cause an increased accumulation of lipids in the liver, which negatively affects insulin’s ability to reduce hepatic glucose...
Excessive proinflammatory cytokine storm could be the main cause of increased vulnerability in this frail population. In patients with diabetes and/or heart disease, a low inflammatory state is often associated with gut dysbiosis. The increase amount of microbial metabolites (i.e., trimethylamine N-...
The study was conducted in Asian subjects who traditionally consume palm oil as the major source of dietary fat, whereas in Europe it is unlikely to account for no more than 5% energy. In conclusion, palmitic acid in the sn-2 position does not adversely affect insulin secretion and glucose ...