Dnmt1, the principal DNA methyltransferase in mammalian cells, is a large and a highly dynamic enzyme with multiple regulatory features that can control DNA methylation in cells. This chapter highlights how insights into Dnmt1 structure and function can advance our understanding of DNA methylation in...
参考: 1.Jurkowska R Z , Jurkowski T P , Jeltsch A . Structure and function of mammalian DNA methyltransferases.[J]. Chembiochem, 2011, 42(19):no-no. 2.谢天立. DNMT抑制剂选择性机制的探究及DNMT1抑制剂的发现[D]....
待解决 悬赏分:1 - 离问题结束还有 Dnmt1 structure and function问题补充:匿名 2013-05-23 12:21:38 null 匿名 2013-05-23 12:23:18 Dnmt 1 结构和功能。 匿名 2013-05-23 12:24:58 Dnmt1结构和作用 匿名 2013-05-23 12:26:38 Dnmt1 结构和功能 匿名 2013-05-23 12:28:18 正...
Dnmt1, the principal DNA methyltransferase in mammalian cells, is a large and a highly dynamic enzyme with multiple regulatory features that can control DNA methylation in cells. This chapter highlights how insights into Dnmt1 structure and function can advance our understanding of DNA methylation in...
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In particular, the structure and function of the rather large TS domain with its multiple roles and interactions remain to be clarified. In this study, we elucidate the complex interplay be- tween UHRF1 and DNMT1. While we could confirm the general role of UHRF1 in recruiting DNMT1 to ...
DNA甲基化基因DNMT1的研究进展
Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD. (2008). DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, ...
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