Wagner S, Green MR (1994) DNA-binding domains: targets for viral and cellular regulators. Curr Opin Cell Biol 6:410–414Wagner S, Green MR 1994 DNA-binding domains: tar- gets for viral and cellular regulators. Curr Opin Cell Biol 6:410-414...
Characterization of the Schizosaccharomyces pombe protection of telomeres 1 (Pot1) DNA-binding domains by biochemical and structural techniquesBiochemistry Characterization of the Schizosaccharomyces pombe protection of telomeres 1 (Pot1) DNA-binding domains by biochemical and structural techniques UNIVERSITY OF...
Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domainsComputational biophysicsNuclear receptorsSAXSHuman estrogen receptor alpha (hERα) is a hormone-responsive nuclear receptor (NR) involved in cell growth and survival that contains ...
网络结合区域 网络释义 1. 结合区域 ...or),转录因子均具备与DNA 相结合之能力,此等结合区域(DNA-binding domains)之基本构型有那四种? xuelele.com.tw|基于2个网页 例句 释义: 全部,结合区域
1.4 DNA-binding Domains DNA-binding domains adopt different structures, and the interaction of these domains with DNA can be established through alpha helices, beta sheets, or disordered regions (Figure 1.3; Pabo and Sauer, 1992). Usually, the DNA-binding domain forms a module that can be sepa...
Pelletier.The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein are functionally distinct. Oncegene . 1998Kim, J., Lee, K. and Pelletier, J. (1998) The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein ...
3.TheDNAbindingdomainsoftheyeastGal4andhumanc-Juntranscriptionfactorsinteractthroughthezinc-finger andbZIPmotifs.Sollerbrant,K.,etal.NucleicAcidsRes.1995,23,588-594. REFERENCES Shipatambienttemperature,freezeuponarrival SHIPCONDITIONS Productshouldbestoredat-20ºC.Aliquottoavoidfreeze/thawcycles ...
DNA-binding domains (DBDs) frequently have N- or C-terminal tails, rich in lysine and/or arginine and disordered in free solution, that bind the DNA separately from and in the opposite groove to the folded domain. Is their role simply to increase affinity for DNA or do they have a role...
Summary: Based on the manual annotation of transcription factors stored in the TRANSFAC database, we developed a library of hidden Markov models (HMM) to represent their DNA-binding domains and used it for a comprehensive classification. The models constructed were applied on the UniProt/Swiss-...
OmpR belongs to a subfamily of at least 50 response regulators with homologous C-terminal DNA-binding domains of approximately 98 amino acids. Sequence homology with DNA-binding proteins of known structure cannot be detected, and the lack of structural information has prevented understanding of many ...