To maintain genome integrity and ensure cell survival, bacteria have evolved several DNA repair pathways to correct different types of DNA damage and non-canonical bases, including strand breaks, nucleotide modifications, cross-links, mismatches and ribonucleotide incorporations. Recent advances in genome...
Genomic integrity of organisms is maintained by the action of DNA repair pathways. Each repair pathway is directed to recognize and remove specific types of damaged or mispaired bases. Usually, repair pathways are highly conserved among eukaryotes and often show a remarkable similarity to bacterial r...
DNA is susceptible to mutation either through errors introduced during replication, chemical or physical modification of the nucleotides, or changes in large-scale nucleic acid structures that serve to protect the integrity of chromosomes. To avoid genome instability, several highly conserved pathways ...
随着基因组技术的出现以及对特定修复途径的了解不断加深，CR 已被证明对主要 DNA 修复途径（如 NER、BER 和双链断裂修复）具有显着影响。With the advent of genomic technology and our increased understanding of specific repair pathways, CR has been shown to have a significant effect on major DNA repair ...
2. Wang Manni, Chen Siyuan, Ao Danyi. Targeting DNA repair pathway in cancer: Mechanisms and clinical application[J]. MedComm, 2021, 2(4). 3. Minlin Jiang, Keyi Jia, Lei Wang, Wei Li, Bin Chen, Yu Liu, Hao Wang, Sha Zhao, Yayi He, Caicun Zhou. Alterations of DNA damage respon...
alterations in DNA repair pathways that arise during tumour development can make some cancer cells reliant on a reduced set of DNA repair pathways for survival. There is evidence that drugs that inhibit one of these pathways in such tumours could prove useful as single-agent therapies, with the...
Mitochondrial DNA repair pathways. J Bioe- nerg Biomembr 1999; 31:391-398.CROTEAU DL, STIERUM RH, BOHR VA. Mitochondrial DNA repair pathways. Mutat Res 1999; 434: 137- 148.CROTEAU, DL., STIERUM, RH., BOHR, VA.; 1999. MItochondrial DNA repair pathways. Mutation Research, 434:137-148...
29.Rosell R, Taron M, Barnadas A, Scagliotti G, Sarries C, Roig B. 2003. Nucleotide Excision Repair Pathways Involved in Cisplatin Resistance in Non-Small-Cell Lung Cancer. Cancer Control. 10(4):297-305.30.Vogel U, Dybdahl M, Frentz G, Nexø BA. 2000. DNA repair capacity: ...
In addition, if DNA repair pathways are deficient, due to inherited mutations or sporadic somatic epimutations in DNA repair genes in replicating somatic cells, unrepaired endogenous and exogenous damages will increase due to insufficient repair. Increased DNA damages would likely give rise to ...
DNA Repair Pathways 測試 方塊 新功能 配對 Direct reversal 點擊卡片即可翻轉 👆 DNA fixed w/o nucleotide replacement 點擊卡片即可翻轉 👆 建立者 victoria_martine17 3年前建立 學生們也學習了 Transcription and translation 51個詞語 BIO EXAM 3