DNA Replication, Repair, and Mutagenesis N.V. Bhagavan, Chung-Eun Ha, in Essentials of Medical Biochemistry (Second Edition), 2015 DNA Polymerase III DNA polymerase I plays an essential role in the replication process in E. coli, but it is not the enzyme that catalyzes the overall DNA polym...
Replication of DNA by DNA Polymerase ITemplate activity of DNA with DNA polymerase I is altered by the action of ionizing radiation. This is explained by the formation of new active and inactive enzyme binding sites on the DNA.R. SAFFHILLJ. J. WEISSNature New Biology...
THE linear DNA of the human adenoviruses type 2 and type 5 (Ad2, Ad5) replicates in the nucleus of permissive cells by a mechanism different from that of chromosomal DNA or papovavirus DNA. Papovaviruses replicate bidirectionally, with both parental stra
(10)Jeffrey D. S. and Foster, P. L. 2005. Polyphosphate kinase regulates error-prone replication by DNA polymerase IV inEscherichia coli. Mol. Microbiology 57:751-761. (11)Storvik, K. A., and P. L. Foster. 2010. RpoS, the stress-response sigma factor, plays a dual role in the re...
(Proceedings of the National Academy of Sciences)发表了题为“DNA polymerase delta governs parental histone transfer to DNA replication lagging strand”的文章,该研究发现聚合酶δ(Pol δ)在DNA复制期间作为关键伴侣蛋白,将亲代组...
Role of the putative zinc finger domain of Saccharomyces cerevisiae DNA polymerase epsilon in DNA replication and the S/M checkpoint pathway. It has been proposed that C-terminal motifs of the catalytic subunit of budding polymerase () () couple to the S/M checkpoint (Navas, T. A., Zheng,...
DNA polymerase III in a complex holoenzyme form is the DNA polymerase that has a central role in DNA replication; however, it is the 5′→3′ exonuclease domain of DNA polymerase I that also possesses RNase H activity, which has an essential role in DNA replication by catalyzing the excision...
(1)DNA 聚合酶 DNA 聚合酶(DNA polymerase)是细胞复制DNA 的重要作用酶。DNA 聚合酶是以DNA 为复制模板,四种脱氧核糖三磷酸为原料,将DNA由5'端点开始复制到3'端的酶。DNA聚合酶只能催化脱氧核糖核苷酸酸加到已有核酸链游离的3’-羟基上,所以需要引物链的存在。DNA 聚合酶是一种模板指导的酶,产物DNA性质完全不...
: any of several polymerases that promote replication or repair of DNA usually using single-stranded DNA as a template Examples of DNA polymerase in a Sentence Recent Examples on the Web This technique, developed in the 1980s, uses the ability of DNA polymerase chains to synthesize new ...
DNA polymerase is an essential component for PCR due to its key role in synthesizing new DNA strands. Consequently, understanding the characteristics of this enzyme and the subsequent development of advanced DNA polymerases is critical ...