Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases. 喜欢 0 阅读量: 13 作者: Abdel-Hafiz,H,A,Heasley,L,E,Kyriakis,J,M,Avruch DOI: 10.1210/mend.6.12.1337144 被引量: 272 年份: 1992 ...
Acetylation regulates transcription factor activity at multiple levels. CREB-binding protein (CBP) possesses an intrinsic acetyltransferase activity capable of acetylating nucleosomal histones as well as several nonhistone prot... E Soutoglou,N Katrakili,I Talianidis - 《Molecular Cell》 被引量: 763...
aSirt1 deacetylase activity has also been implicated in the repair of DNA damage, through its ability to deacetylate the tumor suppressor p53 [26,52], a sequence-specific transcription factor that regulates processes such as the cell cycle, cell death, and DNA repair, in response to a variety...
Furthermore, it was found that the DNA binding activity of the Runt domain is regulated by a reduction/oxidization (redox) mechanism and that its reductively activated state, which is extremely labile, is stabilized by the β subunit. These findings add a new layer to the mechanism and ...
DNA sequence analysis revealed a binding motif for octamer-binding transcription factor 1 (OCT-1) in the deleted fragment. Mutation of this OCT-1 binding motif resulted in a similar effect as the deletion experiment, i.e. it increased the basal promoter activity and abolished the response to ...
Sosic D, Richardson JA, Yu K, Ornitz DM, Olson EN . (2003). Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity.Cell112: 169–180. ArticleCASGoogle Scholar Spicer DB, Rhee J, Cheung WL, Lassar AB . (1996). Inhibition of myogenic ...
Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases. 1992. Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases...
We have examined the activity of the Xenopus heat-shock transcription factor (HSF) in extracts from stressed and unstressed embryos at various stages of development using DNA mobility shift analysis. A specific interaction between HSF and a synthetic oligonucleotide corresponding to the proximal heat-sh...
The reduction in C/EBPalpha binding to alpha-satellite DNA was induced by the co-expression of the transcription factor Pit-1, which removes C/EBPalpha from the heterochromatic compartment, and by the introduction of an altered-specificity mutation into C/EBPalpha that reduces binding to alpha-...
(2001) Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated ... ML Goodson,Y Hong,R Rogers,... 被引量: 0发表: 2018年 Role of SUMO-1-modified PML in nuclear body formation. The tumor-suppressive promyelo...