DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective effects due to its anti-inflammatory, anti-oxidative and anti-apoptotic activities. DL-NBP not only protects against ischemic cere...
Recent evidence indicates that Dl-3-n-butylphthalide (NBP) has the neuroprotective effect in ischaemic brain injury, but whether it has protective effects on SCI or not is largely unclear. Here, we show that NBP prevented BSCB disruption after SCI via inhibition of ER stress. Following a ...
5.Effect of NBP on the Expression of Caspase-3 in Rat after Cerebral Ischemia-reperfuson;丁苯酞对大鼠局灶性脑缺血再灌注损伤后caspase-3表达的影响 6.Neuron configuration and expression of Caspase-9 mRNA、after cerebral ischemia reperfusion,and effect of dl-3n-butyl phtalide in rats丁苯酞对大鼠脑...
Alzheimer’s disease (AD) is the most common form of neurodegenerative disease and most anti-AD drugs have failed in clinical trials; hence, it is urgent to find potentially effective drugs against AD. DL-3-n-butylphthalide (NBP) is a compound extracted from celery seed and is a multiple-t...
* Correspondence: 11956170@pku.edu.cn; Tel.: +86-10-8280-2431 Received: 18 September 2017; Accepted: 14 November 2017; Published: 22 November 2017 Abstract: Dl-3-n-butylphthalide (NBP) is a drug that is used in the treatment of ischaemic stroke. However, to the best of our knowledge,...