Dl-3n-butylphthalide (NBP) is a novel agent and has a potential role on angiogenic activity and a good curative effect against cerebral ischemia. However, the molecular mechanism remains unclear. In order to explore the effect of NBP on the incidence and development of AD, we selected Male ...
白求恩医院发现芹菜提取物DL-NBP能可以对脑损伤起保护作用 一项刊登在影响因子5.076杂志Molecular Neurobiology上题为“TiO2-Nanowired Delivery of DL-3-n-butylphthalide (DL-NBP) Attenuates Blood-Brain Barrier Disruption, Brain Edema Formation, and Neuronal Damages Following Concussive Head Injury”的研究报告中...
白求恩医院发现芹菜提取物DL-NBP能可以对脑损伤起保护作用 一项刊登在影响因子5.076杂志Molecular Neurobiology上题为“TiO2-Nanowired Delivery of DL-3-n-butylphthalide (DL-NBP) Attenuates Blood-Brain Barrier Disruption, Brain Edema Formation, and Neuronal Damages Following Concussive Head Injury”的研究报告中...
DL-3-n-Butylphthalide (DL-NBP), a small molecular compound extracted from the seeds of Apium graveolens Linn (Chinese celery), has been shown to exert neuroprotective effects due to its anti-inflammatory, anti-oxidative and anti-apoptotic activities. DL-NBP not only protects against ischemic cere...
Recent evidence indicates that Dl-3-n-butylphthalide (NBP) has the neuroprotective effect in ischaemic brain injury, but whether it has protective effects on SCI or not is largely unclear. Here, we show that NBP prevented BSCB disruption after SCI via inhibition of ER stress. Following a ...
Objectives: To investigate the neuroprotective effect and mechanism of dl-3-n-butylphthalide (NBP) on rats with brain injury. Methods: A total of 1007-week-old male Sprague-Dawley (SD) rats were randomly divided into 5 groups: sham group, model group, NBP low, med...
Dl-3n-butylphthalide (NBP), a racemic mixture of an optical iso- mer, is extracted from the seeds of Apium graveolens Linn18. It is widely used for its therapeutic effects on ischemic strokes19. It has been shown to possess a range of pharmacological properties includ- ing anti-inflammatory...
目的:观察丁基苯酞(NBP)对大鼠局灶性脑缺血及重灌后海马,纹状体和皮层中TXB2及6-keto-PGF1α含量的影响,方法:尼龙线栓塞法造成大鼠局灶性脑缺血模型,TXB2和6-keto-PGF... 种兆忠,冯亦璞 - 《中国药理学报》 被引量: 0发表: 1997年 丁基苯酞的药理作用及作用机制的研究 丁基苯酞(dl-3-n-butylphthalide,...
目的:阐明正丁基苯酞(dl 3 n butylphthalide,dl NBP)改善缺血脑能量代谢的机制.方法:用分光光度法测定局灶性脑缺血大鼠脑线粒体呼吸链复合酶I,I,II和IV活性的改变... 熊杰,冯亦璞 - 《药学学报》 被引量: 192发表: 1999年 dl-3-正丁基苯酞软胶囊与阿司匹林治疗急性缺血性脑卒中的多中心、随机、双盲双模...
丁苯酞(dl-3-n-butylphthalide,NBP)活性成分为d1-3-正丁基苯酞,为脂溶性药物,可以直接通过血-脑屏障发挥作用.大量的临床及实验室研究已经证明其对缺血性脑血管... 孟然 - 《河北医科大学》 被引量: 9发表: 2015年 dl—3—n—丁基苯酞对右大脑右中动脉阻断大鼠纹状体脑血流的影响 观察dl-3-n-丁基苯酞(...