97 Distribution of Microglia (MG) in the Immature Brain with Isolated Germinal Matrix/Intraventricular Haemorrhage (GMH/IVH): A Combined Mri and Histological ApproachBackground: GMH/IVH remains a prevalent form of injury to immature brain. In the absence of overt complications, haemorrhage may ...
We have examined the distribution of microglia in the normal adult mouse brain using immunocytochemical detection of the macrophage specific plasma membrane glycoprotein F4/80. We were interested to learn whether the distribution of microglia in the adult brain is related to regional variation in the ...
Turnover of resident microglia in the normal adult mouse brain We undertook this study to determine whether the microglia, the resident macrophages of the central nervous system, turn over in the steady-state. The turn... LJ Lawson,VH Perry,S Gordon - 《Neuroscience》 被引量: 935发表: 1992...
The detailed patterns of afferentation to the ammon's horn and dentate gyrus of the hippocampus in the rat were investigated employing the anterograde trac... C Nyakas,PGM Luiten,DG Spencer,... 被引量: 299发表: 1987年 Development of microglia in the postnatal rat hippocampus the regional d...
Deciphering microglia plasticity in glioma Microglia are the innate immune cells of the brain. One of the main characteristics of microglia is its extremely plasticity, which is necessary for them t... D Saidi 被引量: 0发表: 2019年 Abstract LB-156: Increased Notch1 expression suppressed the gr...
Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator i... Multipotent mesenchymal stromal cells (MSCs) decrease the expression of transforming growth factor β1 (TGFβ1) in astrocytes and subsequently decrease...
For example, reported AD-related alterations in ratios of APP alternative transcripts could be attributed to changes in expression of APP in specific neuronal subpopulations, and/or reactive astrocytes and/or microglia. To address this question, we have employed in situ hybridization using biotinylated...
Double immunostaining identified abnormal prion protein in the neuropil and associated with neurons, astrocytes and microglia, but absence in Purkinje cells. The established protocol for the simultaneous immunohistochemical detection of disease-specific prion protein and cellular markers enables detailed ...
Using immunohistochemistry we have mapped the cellular distribution of GPx-1 and have shown it to be in highest levels in microglia and with lower levels in neurons. Only a trace amount was detectable in astrocytes using immunofluorescence and GPx-1 was not detectable in oligodendrocytes. GPx-1 ...
Host microbiota constantly control maturation and function of microglia in the CNS Nat Neurosci, 18 (2015), pp. 965-977 CrossrefView in ScopusGoogle Scholar 22 Y. Ishida, Y. Kurosaka, Y. Murakami, T. Otani, K. Yamaguchi Therapeutic effect of oral levofloxacin, ciprofloxacin, and ampicillin ...