In mature laboratory animals, adverse effects on the lung have been observed after chronic exposure to TCDD and include lesions such as alveolar-bronchiolar metaplasia, hyperplasia of the bronchiolar epithelium,
In 1976 at Seveso, Italy, a chemical plant explosion occurred, marked in the history as “Seveso disaster”. The accident caused the spreading of over 30 kg of TCDD and other chemicals about 18 square kilometers, which was the highest ever-recorded residential human exposure to...
The incidence of uterine squamous cell carcinoma was significantly or marginally increased in the 6 ng/kg core and 100 ng/kg stop-exposure groups of TCDD and in the 300 ng/300 碌g/kg core group that received the binary mixture of PCB126 and 153. The incidence of uterine carcinoma was ...