Summary: In this paper, a course of the disease of a 68year-old patient treated with medigoxin for congestive heart failure is presented. After being withdrawn from his treatment at the hospital, the patient was administered spironolactone and turosemide. The plasma digoxin level at entry was ...
CONTEXT: Digoxin is used in the treatment of patients with cardiac dysfunction, though toxicity sometimes results from the use of this medication. In 1986, the US Food and Drug Administration (FDA) approved a digoxin immune Fab for the treatment of such patients. In 2001, the FDA approved a...
If the assay is sensitive to these substances, consider obtaining a baseline digoxin level before starting Digoxin Tablets and correct post-treatment values by the reported baseline level. Obtain serum digoxin concentrations just before the next scheduled Digoxin Tablets dose or at least 6 hours afte...
Digoxin is a cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
Further research revealed that digoxin regulated Nrf2 at transcriptional level. In in vivo study, we found that digoxin and gemcitabine in combination inhibited tumor growth more substantially when compared with gemcitabine treatment alone in SW1990/Gem-shControl cells-derived xenografts. In the meantime...
The toxicity of digoxin is very important to understand because toxicity is so common. Treatment is to stop giving the drug for a short period, or, if there are severe cardiac arrhythmias, an antibody called Digibind can be given; Digibind binds digoxin and increases the rate of clearance. ...
If the assay is sensitive to these substances, consider obtaining a baseline digoxin level before starting digoxin and correct post-treatment values by the reported baseline level. Obtain serum digoxin concentrations just before the next scheduled digoxin dose or at least 6 hours after the last dose...
Her digoxin level was 3.4 ng/mL when measured by her general practitioner before hospital referral, and 2.9 ng/mL at admission. The woman received treatment with anti-digoxin polyclonal antibody [Digib ... 展开 DOI: 10.1007/s40278-013-0908-9 年份: 2013 ...
Digitalis Intoxication: A Prospective Clinical Study with Serum Level Correlations. New Engl J Med 1971;284:989-997. 4. Dickstein K, Cohen-Solal A, Filippatos G, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis...
During treatment, total and free digoxin were determined using an Abbot TDX analyser and an ultrafiltration technique. ADAF were measured by an enzyme-linked immunosorbent assay. By 1 h after ADAF, total serum digoxin concentrations had risen 12-fold from a pretreatment level of 15.4 nmol l-1...