Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation occurs during development of an organism to produce new specialised cells, and also in adults to ...
Rethinking Differentiation: Stem Cells, Regeneration, and Plasticity | Cell 下部分翻译如下: 细胞命运的可塑性 如果发育是从受孕到死亡的连续过程,那么重要的是要问细胞“功能成熟”或“分化”意味着什么。现代细胞分化概念的起源可以追溯到奥古斯特·魏斯曼 (August Weismann, 1893) 的有影响力的著作《生殖质理论》(...
An ideal alternative would be a technology capable of generating T-lineage cells from multiple sources of stem cells using a simple serum- and stromal cell-free approach that is amenable to large-scale suspension cultures. Here, we report the development of a bead-based in vitro system that su...
Stem cells have long-term self-renewing activity and can commit to multiple celltypes upon differentiation signals. Since Yamanaka and colleagues demonstrated thatthe four DNA-binding transcription factors Oct4, Sox2, c-Myc, and Klf4 transformfibroblasts into a type of pluripotent cells known as indu...
Although studies in vivo revealed promising results in bone regeneration after implantation of scaffolds together with osteogenic progenitor cells, basic q... P Müller,U Bulnheim,A Diener,... - 《Journal of Cellular & Molecular Medicine》 被引量: 290发表: 2008年 Mesenchymal stem cell proliferati...
aThe left eye side of the right eye has not seen, do not know how to comfort only to accompany it with tears 右眼睛的左眼睛边没看见,不会安慰只补充它以泪花[translate] aStem cell proliferation, differentiation, and the 干细胞扩散,分化,和[translate]...
Stem cell - Regeneration, Differentiation, Tissue Repair: Some tissues in the adult body, such as the epidermis of the skin, the lining of the small intestine, and bone marrow, undergo continuous cellular turnover. They contain stem cells, which persist
The distribution of the source of stem cells was found to be biased towards the adult stage, but relatively similar over the embryonic and fetal stages... AN Patel,W Sherman - 《Cell Transplantation》 被引量: 28发表: 2007年 Induced Pluripotent Stem Cells: From the Bedside to the Bench, an...
The method for in vitro differentiation of neuronal stem cells comprises the following: the cells are brought into contact with a substance which inhibits a reaction of the Wnt signal transduction path, and said cells are cultivated in conditions enabling the cells to multiply and/or differentiate....
proliferationin vitro, while a high concentration (5-10 mmol/L) could inhibit cell proliferation (P<0.05). According to the literature and the experimental data, 0.1 mmol/L NaF was selected as the following experimental concentration. The levels of alizarin red S staining were increased after Na...