Differentiation of mouse embryonic stem cells into neural cells on silk fibroin scaffolds小鼠胚胎干细胞结合丝素材料向神经细胞分化的实验研究胚胎干细胞丝素神经细胞The feasibility of embryonic stem cells to combine with silk fibroin for neural differentiation was invaluable and unknown. We suspended the ES ...
However, it is unknown if HEI-OC1 cells can promote the differentiation of embryonic stem cells (ESCs). In this study, we conditioned HEI-OC1 cells to survive in the stem cell culture environment and developed both direct and indirect stem cell co-culture systems. We determined that both ...
The potential of human embryonic stem (hES) cells to differentiate into cell types of a variety of organs has generated much excitement over the possible use of hES cells in therapeutic applications. Of great interest are organs derived from definitive endoderm, such as the pancreas. We have foc...
Embryonic stem cells (ESCs) are pluripotent and capable of indefinite self-renewal in vitro. These features make them a highly advantageous source for deriving any cell type of the central and peripheral nervous system. We describe neural induction of human (h)ESCs, by using the bone morphogenic...
Embryonic stem cells can proliferate indefinitely and are capable of differentiating into derivatives of all three embryonic germ layers in vitro, including the neural lineage. The main objective of this study is to test the effects of neural stem cell conditioned medium on the neural differentiation...
of cells produced by directed differentiation in vitro could be applied to study the cell replacement therapies of disease,etc.This paper elaborated signaling mechanisms regulating self renewal and differentiation on induced differentiation of embryonic stem cells,methods of induced differentiation of ...
采用分阶段诱导小鼠和人胚胎细胞分化的培养体系,用流式细胞仪,免疫组织化学及Wright染色鉴定细胞,探索体外定向诱导小鼠及人的胚胎干细胞(embryonic stem cell,ES)为造... 徐令,乔春平,黄绍良,... - 《科学通报》 被引量: 128发表: 2000年 HOXB4基因在造血干细胞自我更新中的调控作用 造血干细胞(hematopoietic ...
Differentiation and isolation of hepatic-like cells from human embryonic stem cells. Human embryonic stem cells are pluripotent cells that can serve as a cell source for transplantation medicine, and as a tool to study human embryogenesis. ... N Lavon,O Yanuka,N Benvenisty - 《Differentiation...
Hematopoietic stem cells derived from human embryonic stem cells (hESCs) could provide a therapeutic alternative to bone marrow transplants, but the efficiency of currently available derivation protocols is low. In this study, we investigated whether coculture with monolayers of cells derived from mouse...
Polycomb repressive complex 1 (PRC1) is an important regulator of gene expression and development. PRC1 contains the E3 ligases RING1A/B, which monoubiquitinate lysine 119 at histone H2A (H2AK119ub1), and has been sub-classified into six major complexes