Also, in cancer cell proliferation, apoptosis, invasion, and migration abnormal expression of piRNAs are emerging as a crucial regulator hence the role of few piRNAs is being given. Both tRFs and tiRNAs play important roles in tumorigenesis and are promising diagnostic biomarkers and therapeutic ...
Translational Psychiatry www.nature.com/tp ARTICLE OPEN I, robot: depression plays different roles in human–human and human–robot interactions Dandan Zhang 1,2 ✉, Junshi Shen1, Sijin Li1, Kexiang Gao1 and Ruolei Gu 3,4 ✉ © The Author(s) 2021 Socially engaging robots have been ...
This Minireview highlights common and divergent features of RAF paralogs, their signaling outputs, and roles in tumorigenesis.Enrico DesideriAnna Lina CavalloManuela BaccariniCellDesideri E, Cavallo AL, Baccarini M: Alike but different: RAF paralogs and their signaling outputs. Cell 2015, 161:967-...
Gene Ontology (GO) pathway enrichment analysis was used to explore the potential functional changes in each cell subtype in atrophic mucosa. Gene set score analysis was conducted to compare the functional roles of different fibroblast subtypes and functional changes in cell subtypes between the CAG an...
Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atrophic gastritis Lin Lin, Tingxuan Huang, Lizhi Li, Yang Lin, Feng Chen, Ziyi Zheng, Jie Zhou, Yizhe Wang, We...
The roles of FGFRs in vertebrate development have been examined extensively in several species using either or both of mutants and the gene knockdown approach to reveal common and unique functions of the fgfr genes (Xu et al., 1999 and references therein; Scholpp et al., 2004, Yokoi et al...
(ATG) family and beclin-1, play fundamental roles in the autophagy process by participating in the phagophore formation and recruitment of autophagic proteins [17]. On the other hand, microtubule-associated protein light chain 3 (LC3), is another protein involved in elongating, sealing the phago...
36.Rufini A, Tucci P, Celardo I, Melino G. Senescence and aging: the critical roles of p53. Oncogene. 2013; in press. 37.Sepe S, Payan-Gomez C, Milanese C, Hoeijmakers JH, Mastroberardino PG. Nucleotide excision repair in chronic neurodegenerative diseases. DNA repair. 2013; 12:568-...
To examine the subtype-specific roles of PLC-β in GPCR-mediated signaling, we first examined which PLC-β subtypes were expressed in HeLa cells. Western blot analysis revealed that β1 and β3 subtypes of PLC-β are expressed in HeLa cells. No expression of PLC-β2 and PLC-β4 in this...
Shakeel SN, Wang X, Binder BM, Schaller GE (2013) Mechanisms of signal transduction by ethylene: overlapping and non-overlapping signalling roles in a receptor family. AoB Plants 5:plt010. https://doi.org/10.1093/aobpla/plt010 Article CAS PubMed PubMed Central Google Scholar Sisler EC, Se...