Protein-protein interaction networks suggest different targets have different propensities for triggering drug resistance. Syst Synth Biol. 2010;4(4):311-22.Padiadpu J, Vashisht R, & Chandra N (2010) Protein-protein interaction networks suggest different targets have different propensities for ...
Here we show that by introducing mutations on the human protein profilin 1, used here as a test case, the in-cell NMR signals can be recovered. In human cells both specific and non-specific interactions are present, while in bacterial cells only the effect of non-specific interactions is ...
The protein–protein interactions (PPI) among coding genes may have an essential role in cancer incidents and can also be utilized as targets for cancer treatment49. The common DEGs were inserted in the Search Tool for Retrieval of Interacting Genes database (STRING) (version 11.0;https://stri...
Protein–protein interaction (PPI) network analysis was used to predict the potential interactions between gene candidates (Szklarczyk et al., 2017). PPI information of the DEGs was acquired from the STRING database (http://string-db.org). Then, PPI networks were constructed by using Cytoscape...
Protein interactions were filtered based on the combined interaction score from STRING, with a threshold value of 0.9 [[49], [50], [51]]. A clustering analysis was then performed using the ClusterOne application [52] with a minimum size of 3 and automated minimum density, and only clusters...
3.4. Protein–Protein Interaction Analysis Using the STRING online tool, we found 163 nodes with 347 protein–protein interaction (PPI) relationships, accounting for 63.2% of all the common DEGs (Figure 3). The properties of the network were analyzed, indicating that the network of PPIs was rel...
Objectives: This study evaluated the cellular response of primary osteoblasts exposed to two different presentations of a low-temperature non-sintered deproteinized bovine bone matrix (DBBM). Materials and methods: Six different baths of a commercially available DBBM block (Bonefill® Porous Block) ...
Protein-protein interaction analysis Using gene sets from two different comparison groups, protein-protein interaction (PPI) networks were constructed using STRING v.10.5 dataset [29]. Only first gene interaction with a highest confidence of> 0.9 and without disconnected nodes was selected. PPI netw...
EVs: Extracellular vesicles MI: Myocardial infarction nEVs: Kidney-derived EVs NTA: Nanoparticle tracking analysis PPI: Protein-protein interaction ROS: Reactive oxygen species TEM: Transmission electron microscopy References Mc Namara K, Alzubaidi H, Jackson JK. Cardiovascular Disease as a ...
All the DAP database accession from different comparison groups were searched respectively using STRING database (https://www.string-db.org/) for protein–protein interactions. Based on the confidence score > 0.7 (high confidence), the interaction network of DAPs was obtained. In order to ...