GABAergic input through GABAB receptors is necessary during a perinatal window to shape gene expression of factors critical to reproduction such as Kiss1 We demonstrate that ARC Kiss1 expression is chronically downregulated in males and that the normal sex difference in AVPV/PeN Th expression is abo...
In a recent study [Gordon et al., Neuroscience, 69 (1995) 345鈥 349.] evaluating interaction between the GABA B agonist baclofen and opiates with respect to postoperative analgesia we found that females receiving pentazocine for the treatment of postoperative pain showed better analgesia than did ...
A molecule facilitating fast signal transmission between neurons. GABA inhibits certain neurons, reducing their activity. 7 Neuromodulator A chemical adjusting the strength of synaptic transmission. Serotonin serves as a neuromodulator affecting mood. 6 Neurotransmitter Neurotransmitters are chemical messengers...
The main differences between diazepam and alprazolam are how long they last in the body and the forms they come in. While diazepam...
What's the difference between the primary motor cortex and the prefrontal cortex?Question:What's the difference between the primary motor cortex and the prefrontal cortex?Answer and Explanation: Become a member and unlock all Study Answers Start today. Try it now Create an accou...
and the 3′ UTR of the murine Htr2c gene was amplified by PCR from R1 ES cells [(129X1/SvJ × 129S1)F1 genetic background] and cloned into a plasmid for insertion of a FRT-NEO-FRT-IRES-CRE cassette between the STOP codon and the polyadenylation site, as previously described [17]....
[Action mechanism of adamantamines: do their activity on glutamatergic receptors intervene in the expression of their pharmacological profile?] Recent data on the aptitude of adamantamines to inhibit or to stimulate glutamatergic (NMDA) neuromediation, to display anti-GABAergic and antiglycinergic ...
Purpose of study is revealing significant differences in serum proteomes in schizophrenia and bipolar disorder (BD). Quantitative mass-spectrometry based proteomic analysis was used to quantify proteins in the blood serum samples after the depletion of s
This will activate and expand pathogenic islet Ag-specific T cell populations [19, 20] and eventually the natural balance between auto-reactive T cells and their regulatory counterparts is disturbed, leading to tolerance breakdown and a progressive β-cell loss (Figure 1). The immanent diminished ...
In untreated LCLs, our results overall suggest a divergence between mRNA (for example, gene transcription) and protein (for example, RNA translation in proteins) for the same genes. Pathway analysis of the LCL transcriptome revealed, among others, over-expression of ESC/E(Z) complex genes (an...