Dendritic cells (DCs) are professional antigen-presenting cells located in the skin, mucosa and lymphoid tissues. Their main function is to process antigens and present them to T cells to promote immunity to foreign antigens and tolerance to self antigens. They also secrete cytokines to regulate...
Classical DCs include type 1 and type 2 subsets, which can detect different pathogens, produce specific cytokines and present antigens to polarize mainly naive CD8+ or CD4+ T cells, respectively. By contrast, the function of plasmacytoid DCs is largely innate and restricted to the detection of ...
Dendritic cells (DC), professional antigen-presenting cells of the immune system, exert important functions both in induction of T cell immunity, as well as tolerance. It is well established that the main function of immature DC (iDC) in their in vivo steady-state condition is to maintain per...
Dendritic cells: function 1 (WS-024a).EBSCO_AspInternational Immunology
Control of myeloid dendritic cell differentiation and function by CD1d-restricted (NK) T cells. While regulating a wide variety of immunologic responses, the precise immunologic functions of CD1d-restricted (NK) T cells are not well defined. Notably, ... FK Racke,M Clare-Salzer,SB Wilson - ...
The cells he discovered, dendritic cells (DCs), were named for their long projections that made them resemble the dendrites of nerve cells, which was the function Langerhans assigned to them at that time. The true role of DCs as powerful antigen-presenting cells (APC) was elucidated by Ralph...
The chemotherapeutic agent topotecan differentially modulates the phenotype and function of dendritic cells immune cell functions, we asked for potential effects of TPT on dendritic cells (DCs), the main antigen-presenting cell population of the immune system... Stefanie,Trojandt,Diana,... - 《Cance...
4.1.1Effect on dendritic cells DCs are bone marrow-derived immuneaccessory cellsthat are found in epithelial andlymphoid tissuesthat are morphologically characterized by thin membranous projections. They also function as APCs for nativeT lymphocytes. Different macrofungi metabolites especiallyβ-d-glucans ...
Multiple sclerosis (MS) is the most common chronic inflammatory demyelinating disorder of the central nervous system characterized by infiltration of immune cells and progressive damage to myelin sheaths and neurons. There is still no cure for the disease, but drug regimens can reduce the frequency ...
Dendritic cells (DCs) are key regulators of both the innate and adaptive arms of the immune system. They are considered the most potent antigen-presenting cells and, as such, are the main orchestrators of adaptive immune responses against invading pathogens or aberrant cells. The potential of the...