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树突状细胞Dendritic cells 英文学习资料.pptx,Dendritic cellsDendritic cells (DCs) are professional antigen-presenting cells that inform the fight against invasive pathogens while enforcing tolerance to self- and harmless environmental antigens. They captu
The workshop dealt with the increasingly important field of defining the role of dendritic and Langerhans cells in immunoregulation. Many basic concepts and facts are still to be evaluated within the growing body of evidence that points to a central role of these cells in initiation and regulation...
Dendritic cells (DCs) primed with tumor antigens (Ags) can stimulate tumor rejection. This study was aimed at evaluating the polarization of T-cell respons... J Galea-Lauri,JW Wells,D Darling,... - 《Cancer Immunology & Immunotherapy》 被引量: 136发表: 2004年 加载更多来源...
Preparation of cytosolic and nuclear extracts. Cells were incubated with lysis buffer (10 mM HEPES, pH 7.4, 10 mM NaCl, 1.5 mM MgCl2, 0.5 mM DTT, 0.2% Nonidet P-40, and 0.2 mM PMSF) at 4 °C for 15 min, and centrifuged at 500 × g for 10 min at 4...
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have numerous shared characteristics between mice and humans. Human counterparts of mouse DC progenitors have been identified by their shared transcriptional signatures
It is being increasingly acknowledged that immune cells depend on certain metabolic traits to perform their functions and that the extracellular environment can influence cell metabolism and vice versa. Dendritic cell (DC) subsets traffic through highly
Abstract In 1868, Paul Langerhans discovered the first immune cell during a study of the skin. The cells he discovered, dendritic cells (DCs), were named for their long projections that made them resemble the dendrites of nerve cells, which was the function Langerhans assigned to them at that...
Immune checkpoint blockade therapies have shown clinical promise in a variety of cancers, but how tumor-infiltrating T cells are activated remains unclear. In this study, we explore the functions of PD-L1 on dendritic cells (DCs), which highly express PD
Dendritic cells (DC) in the lung that induce Th17 differentiation remain incompletely understood, in part because conventional CD11b+ DCs (cDC2) are heterogeneous. Here, we report a population of cDCs that rapidly accumulates in lungs of mice following h