Chemotaxis and activation markers of dendritic cells in myocardial infarctionAn important role of monocytes in the coronary artery disease (CAD) is well documented. Increased number of circulating monocytes is associated with higher incidence of CAD. Both environmental and genetic factors influence mono...
cellscanbebroadlycategorizedbased ontheexpressionpatternsoanumbero cellsuracemarkersintomyeloid-derived, lymphoid-derived,dermal-derived,and plasmacytoidDC. DendriticCellMarkers R a t I g G 2 a P E - C y 7 Gr-1FITCGr-1FITC C D 2 0
The results demonstrate few or no CD1a-positive putative dendritic cells and minimal or no expression of the dendritic cell activation markers. Both dendritic cell number and dendritic cell activation appear substantially deficient in human breast cancers, regardless of tumour histological grade....
B cells are prominent components of human solid tumours, but activation status and functions of these cells in human cancers remain elusive. Here we establish that over 50% B cells in hepatocellular carcinoma (HCC) exhibit an FcγRIIlow/−activated phenotype, and high infiltration of these cel...
cellscanbebroadlycategorizedbased ontheexpressionpatternsoanumbero cellsuracemarkersintomyeloid-derived, lymphoid-derived,dermal-derived,and plasmacytoidDC. DendriticCellMarkers R a t I g G 2 a P E - C y 7 Gr-1FITCGr-1FITC C D 2 0 5 ( D E C 2 0 5 ) P E - C y 7 MouseDEC205(...
Dendritic cells are a complex group of mainly bone marrow derived cells that possess significant ability to take up, process, and present soluble antigens to responder cells in the lymphoid tissues. Characterization of DC surface markers has been a difficult task owing to the lack of appropriate ...
The primary objective of this study was to determine whether markers of differentiation and activation of the Akt pathway are associated with metastasis in... JM Mcdonald,CE Pelloski,A Ledoux,... - 《Clinical Cancer Research An Official Journal of the American Association for Cancer Research》 ...
Assessment of activation of dendritic cells can be used to study the effect of agonists and antagonists on the immune response controlled by dendritic cells, for example in the study of biotherapeutics targeting the innate immune system. Maturation can be measured by looking at upregulation of MHC...
What are dendritic cells? Dendritic cells (DCs) play a pivotal role in the innate detection of pathogens and the subsequent activation of the adaptive immune response. DCs initiate the adaptive response by presenting antigenic peptides on major histocompatibility complex (MH...
activation states of a single subtype. There are different functional phenotypes based on cytokine and metabolite production and the expression ofcell surface markersand thus DCs are able to adapt to various environmental stimuli. DC subtypes includeplasmacytoid DCs(pDCs),Langerhans cells, and ...