In many countries, e.g., in Germany, Mo-DCs are legally considered medicinal products, which must be produced under Good Manufacturing Practice (GMP) conditions by an institution holding an official production license. Plastic adherence, immunomagnetic selection of CD14+ monocytes and depletion of ...
Department of Neurology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg-University of Mainz,Rhine Main Neuroscience Network (rmn2), Langenbeckstrasse 1, 55131, Mainz, Germany Felix Lüssi, Frauke Zipp & Esther Witsch Corresponding authors Correspondence...
Dendritic cell vaccination and other strategies to tip the balance of the immune system : DC2007 5th International Meeting, July 16-18, Bamberg, Germany. Niels,Schaft,Katrin,... - 《Cancer Immunology Immunotherapy Cii》 被引量: 9发表: 2008年 DC2007: 5th International meeting on dendritic cell...
are members of the Deutsche Forschungsgemeinschaft Excellence Cluster ImmunoSensation in Bonn, Germany, and are supported by grant SFB704. W.K. is supported by the NRW-Rückkehrerprogramm of the German state of Northrhine-Westfalia. The authors thank G. Gasteiger, N. Garbi and their laboratory...
coerythrin,Germany) 被引量: 79发表: 0年 Tumor necrosis factor promotes human T-cell development in nonobese diabetic/severe combined immunodeficient mice Mobilized peripheral blood cellsHematopoietic stem cellsA major problem after clinical hematopoietic stem cell transplantations is poor T-cell reconsti...
OT-I and OT-II cells were harvested from spleens of OT-I56 and OT-II57 TCR transgenic mice, and enriched with mouse CD8+ or CD4+ T cell magnetic bead isolation kit (Miltenyi Biotec, Bergisch Gladbach, Germany), respectively. OT-I and OT-II cells were stained with 5 μM CellTrace...
Immunization-induced antigen archiving enhances local memory CD8+ T cell responses following an unrelated viral infection ArticleOpen access21 March 2024 Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity ...
DCPs provide a cell therapy platform alternative to moDCs Most preclinical and clinical experimentations with antigen-loaded DCs used moDCs3. We then investigated whether transgenic expression of IL-12 and FLT3L would confer upon moDCs the ability to expand T cells and control tumor growth in ...
(Th1) and natural killer cell responses through IL‐12. The secretion of XCL1, the unique known ligand of XCR1, by memory T cells, NK cells [18], and NKT [19] cells allows these cells to interact with cDC1s. These immune populations are characterized by the secretion of interferon-γ...
Institute of Immunology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany Tim Worbs, Swantje I. Hammerschmidt & Reinhold Förster Corresponding author Correspondence to Reinhold Förster. Ethics declarations Competing interests The authors declare no competing financial interests...