abilitytoinitiatenaïveTcellresponses tocognateantigen.DCsorchestratethe unctionaloutcomeoTcellactivation dependingonthetypeoDCpresenting antigenandthephysiologicalconditions inwhichDC:Tcellinteractionstakeplace. DCsarethoughttoplayacriticalroleinthe diferentiationoregulatoryTcellsandthe ...
After uptake, Tax-induced expression of DC activation markers MHC class I and II, and costimulatory molecules as well as the DC maturation marker, CD83. Tax has also promoted the production of major immune-directing cytokines IL-12, TNF-α , and proinflammatory chemokines MIP-1α, MIP-1β,...
The mouse dendritic cell marker CD11c is down-regulated upon cell 36 activation through Toll-like receptor triggering. Immunobiology.2013;218:28-39. 37 38... Sándor,Kristóf,Paréj,... - 《Immunobiology Zeitschrift Fur Immunitatsforschung》 被引量: 0发表: 2013年 Pathogenic TH17 inflammation is...
We purified the FcγRIIhighand FcγRIIlow/−B cells from HCC tumours. The purities of B cells we used were >98%, as assessed by determining the expression of myeloid cell marker CD33 and T-cell marker CD3 (Supplementary Fig. 1c). The FcγRIIlow/−B cells, undergoing IL-21 plu...
We have therefore examined CD1a expression as a marker for dendritic cells, together with CMRF-44 and -56 as markers of dendritic cell activation status, in 40 human breast cancers. The results demonstrate few or no CD1a-positive putative dendritic cells and minimal or no expression of the ...
HumanILT7(novelpDCmarker,CD85g) MouseMHCClassIH-2K b /SIINFEKL:Stainingofunpulsed (bluehistogram)orOVASIINFEKL-peptidepulsed(pink histogram)C57BL/6splenocyteswithPEanti-mouseMHC classIH-2K b /SIINFEKL(eBio25-D1.16)(cat.no.12-5743).Total viablecellswereusedforanalysis. MouseMHCClassIH-2K...
Monocyte Cell Overview Learn about monocytes function, development and role the innate immune system. Immune Cell Guide Find detailed marker information for immune cell types and subtypes. T-helper cell paradigm poster Discover how Naive Th cells play a central role in modu...
There is no single cell marker that is known to be expressed exclusively by DCs, and so a combination of the presence and absence of various proteins can be used to identify them. A combination in expression of CD1c, CD11c, CD16, CD45, CD141, CD370 (CLEC9A), HLA-DR, and lineage ex...
CD11c, which is the prototypical cell-surface marker for DCs present in the spleen andLN, is insufficient to specifically identify DCs in peripheral tissues. Albeit at somewhat lower levels, CD11c is expressed byeosinophils,43dNK cells,19,44decidual MHCII+macrophages,42and decidual MHCII+...
Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma. 靶标信息 CD35 (CR1, Complement Receptor 1) is a cell membrane-bound, monomeric glycoprotein a...