107Background: Malignant transformation increases cellular demand for fatty acids (FA). Many cancers show increased expression of fatty acid synthase (FASN); FASN catalyzes the de novo synthesis of the FA palmitate. While research has focused on FASN and de novo tumor FA synthesis, observations su...
Here, we interrogated the 3′-end of SARS-CoV-2 for GAIT element-like RNA elements and report a novel pan-element. Importantly, together with stimulus-dependent, trans-acting binding proteins, sgRNAs bearing the element form a translational regulon that enhances translation. Targeting this element...
We demonstrate that PM2.5concentrations are exceptionally high throughout the trans- and upper-IGP, but its composition differs substantially due to the local origins of PM components. Despite the spatial variability in PM composition, species driving OP are mainly organic in nature across all sites ...
The trans-differentiation capacity of c-Myc is mediated through induction of REST, a neuronal differentiation repressor [136]. Importantly, the cells that replaced c-Myc with L-Myc became resistant to Aurora kinase inhibition [136]. These observations support the view that the plasticity between ...
The trans-differentiation capacity of c-Myc is mediated through induction of REST, a neuronal differentiation repressor [136]. Importantly, the cells that replaced c-Myc with L-Myc became resistant to Aurora kinase inhibition [136]. These observations support the view that the plasticity between ...
3.2. Chlorogenic Acids Chlorogenic acids (CGAs) consist of a family of esters formed between trans-cinnamic acids, such as caffeic acid and ferulic acid, with quinic acid [60]. The ester linkage is formed between the carboxyl group of trans-cinnamic acids and all four of the quinic acid ...