Does side make any difference in long-term follow-up? Abcd-Arquivos Brasileiros De Cirurgia Digestiva-Brazilian Archives of Digestive Surgery. 2019;32(4):e1479. Imperial R, Ahmed Z, Toor OM, Erdoğan C, Khaliq A, Case P, et al. Comparative proteogenomic analysis of right-sided colon ...
In the context of Biology, define the following term and give an example: Heterozygous. Define the term missense mutation. Define the term enhancer and explain how it is associated with control of gene expression. Define the term biology in your own words What is the best definition of biology...
Define gene, trait, and chromosome. Relate heritability to the theory of evolution. Define the term genetics. Describe the different types of genes and traits. Explain why information on both the heritability of a trait and the strength of selection on a trait i...
Drug resistance is a principal limitation to the long-term efficacy of cancer therapies. Cancer genome sequencing can retrospectively delineate the genetic basis of drug resistance, but this requires large numbers of post-treatment samples to nominate causal variants. Here we prospectively identify geneti...
Fig. 4), suggesting that sCD206 is unstable in urine upon long-term storage. Thus, urinary sCD206 will likely not be a viable marker for glomerulonephritis. In line with previous findings, we found distinct macrophage phenotypes including CD206+CD163-, CD163+CD206- and CD163+CD206+ ...
we combine genomic sequencing and high-content imaging approaches on iPSCs from 297 unique donors to investigate the relationship between genetic variants and cellular morphology to map what we term cell morphological quantitative trait loci (cmQTLs). We identify novel associations between rare protein ...
Here, we investigate the role of WIZ at CTCF binding sites in the genome and report a role for WIZ distinct from that with G9a and GLP in heterochromatin formation. We identify a function for WIZ in DNA loop architecture, regulation of gene expression, and maintenance of stem cell identity...
PPARG generated a rapid and short-term response while maintaining a gene activator role. By contrast, LXR signaling was prolonged, with initial, predominantly activating functions that transitioned to repressive gene regulatory activities at late time points. Through the use of a multi-tiered strategy...
2 Kaplan Meier overall survival curves for chromosome 1q status (a, b), TNC (c, d) and WHO grade (e, f) in the recent (1992–2014; a, c, e) and the entire cohort (1965–2014; b, d, f) long-term follow-up, as well as the possibility to rescue patients with recurrence, ...
6a) and that samples with increased lack of p53 binding consistently showed decreases in p53 target gene RNA expression (Extended Data Fig. 6b). We independently re-derived the oncogenicity–immunogenicity trade-off by comparing the inferred immunogenicity to our scores for lack of binding (...