An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASEdoi:10.1105/tpc.113.113456Orthodox seeds are capable of withstanding severe dehydration. However, in the dehydrated state, Asn and Asp residues in proteins can...
thaliana DEAD-box ATP-dependent RNA helicase 7 (also known as AtRH7; AT5G62190) was previously shown experimentally to be localized to the nucleus (Lorković et al. 1997). This evidence supports our phylogenetic analysis suggesting that GUCT-containing RNA helicases are clearly organelle ...
In the absence of ATP and RNA, these two RecA-like domains of the helicase core move freely and are flexible with respect to each other (open conformation). The collaborative binding of ATP and RNA, stimulates these two domains to form a closed position (closed conformation), to induce ATP...
DEAD-box RNA解旋酶是一个依赖ATP的RNA解旋酶大家族,广泛地存在于从原核生物的细菌到真核生物的酵母、植物和动物中。 更多例句>> 4) DEAD box DEAD盒 1. The ATP dependent RNA helicases of the DEAD box family, involved in almost every cellular process of RNA metabolism, play many essential roles...
Memberso,theDEADbox,amilyo,RNAhelicasesareknowntobeinvolvedinmostcellularprocessesthatrequiremanipulationo,RNAstructureand,inmanycases,exhibitother,unctionsinadditiontotheirestablishedATP-dependentRNAhelicaseactivities.Theythusplaycriticalrolesincellularmetabolismandinmanycaseshavebeenimplicatedincellularproli,erationand...
Although a number of ATP-dependent RNA helicases are important for constitutive RNA splicing, no helicases have been implicated in alternative RNA splicing... A Honig,D Auboeuf,MM Parker,... - 《Molecular & Cellular Biology》 被引量: 174发表: 2002年 A DEAD-box protein alone promotes group...
transcriptional level. RNA helicases are involved in the formation of cytoplasmic ribonucleoprotein (RNP) granules and RNA silencing. A highly conserved central domain is characteristic of DEAD-box RNA helicases and determines their basic biological activity in ATP-dependent unwinding of short RNA ...
DDX3 is a highly conserved member of ATP-dependent DEAD-box RNA helicases with multiple functions in RNA metabolism and cellular signaling. Here, we describe a novel function for DDX3 in regulating the mitochondrial stress response in the parasitic protozoanLeishmania.We show that genetic inactivatio...
RNA helicases from the DEAD-box family are found in almost all organisms and have important roles in RNA metabolism. They are associated with many processes ranging from RNA synthesis to RNA degradation. DEAD-box proteins use the energy from ATP hydrolysis to rearrange inter- or intra-molecular...
7 The catalytically deficient mutant Ded1DQAD forms constitutive stress granules, without being compromised for RNA or ATP binding. a, Ded1DQAD–mCherry, but not wild-type Ded1–mCherry, forms stress granules (arrows) in unstressed cells. Images are representative of more than three independent ...