Min WangUSUS5989858 * 1997年10月28日 1999年11月23日 Smithkline Beecham Corporation Dead-type ATP-dependent RNA helicase (DbpB) from Staphylococcus aureusUS5989858 * Oct 28, 1997 Nov 23, 1999 Smithkline Beecham Corporation Dead-type ATP-dependent RNA helicase (DbpB) from Staphylococcus aureus...
Here we show that members of the large and highly abundant family of RNA-dependent DEAD-box ATPases (DDXs)3 are regulators of RNA-containing phase-separated organelles in prokaryotes and eukaryotes. Using in vitro reconstitution and in vivo experiments, we demonstrate that DDXs promote phase ...
Although a number of ATP-dependent RNA helicases are important for constitutive RNA splicing, no helicases have been implicated in alternative RNA splicing... A Hönig,D Auboeuf,MM Parker,... - 《Mol.cell.biol》 被引量: 118发表: 2002年 The DEAH‐box protein PRP22 is an ATPase that ...
Keywords:RNAhelicase;DEAD boxRNAhelicase;neoplasm 1 引言 RNA解旋酶有 9个保守基序,其中含有能够结 合 RNA和 NTP的结构域.RNA解旋酶与 RNA结 合后可以激活 NTP酶的活性,水解 NTP产生能量促 使双链 RNA解链.DEAD boxRNA解旋酶(DEAD boxRNAHelicase,DDX)是 RNA解旋酶超家族成员 之一,因为其第二个基序含有...
DDX3 is a highly conserved member of ATP-dependent DEAD-box RNA helicases with multiple functions in RNA metabolism and cellular signaling. Here, we describe a novel function for DDX3 in regulating the mitochondrial stress response in the parasitic protozoanLeishmania.We show that genetic inactivatio...
transcriptional level. RNA helicases are involved in the formation of cytoplasmic ribonucleoprotein (RNP) granules and RNA silencing. A highly conserved central domain is characteristic of DEAD-box RNA helicases and determines their basic biological activity in ATP-dependent unwinding of short RNA ...
DDX43 is an ATP-dependent RNA helicase According to its primary protein sequence, DDX43 belongs to the DEAD-box protein family of RNA helicases (16); thus we started to characterize its RNA unwinding activity. Using a 5′-tailed 13-bp duplex RNA that is commonly used with the DEAD-box ...
thaliana DEAD-box ATP-dependent RNA helicase 7 (also known as AtRH7; AT5G62190) was previously shown experimentally to be localized to the nucleus (Lorković et al. 1997). This evidence supports our phylogenetic analysis suggesting that GUCT-containing RNA helicases are clearly organelle ...
Kottayil Padmanabhan1,4, Ouafa Zghidi-Abouzid1,4, Mukesh Samant2, Carole Dumas1, Bruno Guedes Aguiar1, Jerome Estaquier1,3 and Barbara Papadopoulou*,1 DDX3 is a highly conserved member of ATP-dependent DEAD-box RNA helicases with multiple functions in RNA metabolism and cellular signaling...
DEAD框肽5(DDX5)重组蛋白 Recombinant DEAD Box Polypeptide 5 (DDX5) G17P1; HLR1; HELR; HUMP68; p68; Asp-Glu-Ala-Asp Box Polypeptide 5; Probable ATP-dependent RNA helicase DDX5 物种 Homo sapiens (Human