FUT8 catalyzes the transfer of a fucose residue from GDP-fucose to N-glycans residue. Defucosylated IgG1 antibodies produced by FUT8(-/-) cells showed increased binding affinities to human Fc gamma RIIIa and higher activities in mediating antibody-dependent cellular cytotoxicity, comparing with ...
This review will focus on FUT8, the enzyme responsible for core fucosylation in mammals and the strategies that have been developed for the synthesis of core fucosylated N-glycans have been synthesized so far.CalderonAngie D.Lei LiWangPeng G....
Inhibition of human hepatocellular carcinoma cell migration by fucosylated glycans Is mediated by IL-8SMMC-7721 hepatocellular carcinoma cells(HCC) were incubated with fucosylated glycoproteins that had been isolated from retinoic acid-treated cells by affinity chromatography.HCC migration was significantly ...
fucosylated glycanslectin histochemistrymorphometryBulletin of Experimental Biology and Medicine - We performed a comparative analysis of the expression of fucosylated glycans and morphometric characteristics of the terminal villi of the placenta,...
core fucosylationfucosylationfucosyltransferasesalpha-1,6-fucosyltransferaseFUT8ICS-28specificityspecificity studies-glycans have been synthesized so far.doi:10.1515/pac-2016-0923Calderon, Angie D.Li, LeiWang, Peng G.Pure & Applied Chemistry