动植物基因组从头测序(Whole-genome de novo sequencing of plants and animals) 基因组从头测序也叫de novo测序,是指对基因组序列未知或没有近源物种基因组信息,某个物种对其不同长度基因组DNA片段及其文库进行序列测定,然后用生物信息学方法进行拼接、组装和注释,从而获得该物种完整的基因组序列图谱。 一、技术路线...
Reference guided re-sequencing is a lot cheaper and easier to do with today’s technology. image.png 参考基因组是什么? 参考基因组是来自一个个体的父本和母本基因组的嵌合体 二倍体基因组:Diploid genome 参考基因组:Reference genome 人类参考基因组是来自多个匿名个体的复合基因组 image.png 那么是来自每...
De novo Whole Genome Sequencing of Olive Tree (Olea europaea L.)Turgay Unver
BGI has been providing de novo whole genome sequencing for over 20 years and are responsible for the initial publication of countless de novo genomes across a huge variety of species in the world's leading journals. We offer a complete suite of technologies to support your...
名词解释 De novo :拉丁文,从头开始的意思,de nove测序则是指在不需要任何参考序列的情况下对某一物种进行基因组测序,然后将测得的序列进行拼接、组装,从而绘制该物种的全基因组序列图谱。 重测序概念 :重测序是全基因组重新测序的简称,是指是对已知基因组序列的物种
真菌全基因组从头测序( Fungi Whole Genome de novo Sequencing ),是指对基因组序列未知或无近缘物种基因组信息的某个物种,构建不同插入片段的基因组 DNA 文库并对文库进行序列测定,然后利用生物信息学方法进行拼接、组装和注释,从而获得该真菌的全基因组序列图谱。
Whole Genome Sequencing, de Novo Assembly and Phenotypic Profiling for the New Budding Yeast Species Saccharomyces jureievolution, fitness, PacBio, translocation, SaccharomycesSaccharomyces sensu stricto complex consist of yeast species, which are not only important in the fermentation industry but are ...
Whole-genome de novo sequencing and assembly of S. fibuligera KJJ81 and KPH12 The WG de novo assemblies of S. fibuligera KJJ81 and KPH12 were produced from long-read single-molecule real-time and Illumina sequence data (Additional file 2: Tables S1–S4, Additional file 3: Figure S2). Th...
目前,研究热点主要集中于具有生产效益和经济价值的性状上,研究方向涉及果实发育成熟、特异代谢产物合成、农艺性状(产量、品质)、园艺性状(花形、花期)、植株病虫抗性等方面。通过基因de novo测序可以一次鉴定到目标性状的多个相关基因,发现新的基因位点,揭示性状形成和调控的遗传机制,为进一步的验证和应用提供指导。
他们的发现发表在题为“De novo mutations identified by whole-genome sequencing implicate chromatin modifications in obsessive-compulsive disorder.”的一篇论文中。这项研究是第一个对患有强迫症的家族进行全基因组新发突变分析。 之前的 GWAS 已经提出了强迫症遗传力和新发突变之间的联系,或者由于亲本生殖细胞(...