首页/癌基因/ DCLRE1C 该基因编码一种参与v(d)j重组和dna修复的核蛋白。该编码蛋白具有单链特异性的5'-3'外切酶活性,在5'和3'的外突和发夹上也表现出内切酶活性。这种蛋白质还可以调节细胞周期,以应对dna损伤。该基因突变可导致阿萨巴扫描型严重联合免疫缺陷(scida)和大网膜综合征。选择性剪接导致多个转录变...
7,8 Larger deletions in the exons (1–4) and a nonsense founder mutation results in loss function in DCLRE1C. However, hypomorphic mutations have also been reported in leaky SCID with residual protein function. DCLRE1C encodes ARTEMIS, a nuclease which is single-stranded with- 5′-3′ ...
11747-1-AP targets DCLRE1C in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications WB, ELISA Application Description Tested Reactivity human, mouse, rat Immunogen DCLRE1C fusion protein Ag2343 种属同源性预测 Host / Isotype Rabbit / IgG Class Polyclo...
DCLRE1C 导读 基因简介 中英文全称:DNA交联修复1C(PSO2 同源物, 芽殖酵母) DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae) 分布:核 活性:镁离子结合|内切核酸酶|外切核酸酶|水解酶 参与:DNA修复|DNA重组|免疫应答 病变:Omenn 综合征(组织 细胞性网状细胞增多)|严重联合免疫缺陷, Athabascan 型...
产品名称:DCLRE1C Antibody 产品型号:abx004292 产品展商:其它品牌 产品文档:无相关文档 简单介绍 DCLRE1CAntibody DCLRE1C Antibody的详细介绍 DCLRE1CAntibodyis a Rabbit Polyclonal antibody against DCLRE1C. This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair...
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiencyReisli, IsmailTurkish Journal of Immunology
产品名称:DCLRE1C Antibody 产品型号:abx112115 产品展商:其它品牌 产品文档:无相关文档 简单介绍 DCLRE1CAntibody DCLRE1C Antibody的详细介绍 Dna Cross-Link Repair 1C (Pso2 Homolog, S. Cerevisiae)Antibodyis a Rabbit Polyclonal antibody against Dna Cross-Link Repair 1C (Pso2 Homolog, S. Cerevisi...
产品名称:DCLRE1C Antibody 产品型号:abx218453 产品展商:其它品牌 产品文档:无相关文档 简单介绍 DCLRE1CAntibody DCLRE1C Antibody的详细介绍 DCLRE1CAntibodyis a Rabbit Polyclonal against DCLRE1C. TargetDCLRE1C ReactivityHuman, Mouse, Rat
该Immunotag™ DCLRE1C Antibody产品厂家推荐的运输条件为:蓝冰运输。保存条件具体查看G-Biosciences提供的产品说明书 其他 G-Biosciences是一家专注于蛋白质组学研究的美国公司,产品广泛应用于学术研究和工业制造领域,包括:蛋白质检测、样品制备、电泳、蛋白质印迹、质谱、测定开发、抗体生产和蛋白质纯化等。目前,G-...
该DCLRE1C / ARTEMIS (aa482-495) 抗体(DCLRE1C / ARTEMIS (aa482-495) antibody)产品的背景资料详情,请查看Covalab提供的产品说明书。 其他 Covalab位于法国,自1995年公司成立以来,在抗体开发和生产方面拥有卓越的经验。Covalab提供超过15000种产品,包括抗体和试剂盒。拥有多种针对流行和罕见靶标的一抗,涉及多...