DAPT基础信息 产品名:DAPT;γ-分泌酶抑制剂;γ分泌酶抑制剂;gamma-Secretase inhibitor;gamma Secretase inhibitor CAS号:208255-80-5 结构式:C[C@@H](C(=O)N[C@H](c1ccccc1)C(=O)OC(C)(C)C)NC(=O)Cc2cc(cc(c2)F)F 分子式 :C23H26F2N2O4 分子量:432.47 闪点:324.1±31.5 °C 沸点:612.2±...
别名DAPT (GSI-IX), Gamma-Secretase Inhibitor IX, CHEBI:86193, MFCD04974585 中文名N/A 化学式C23H26F2N2O4 分子量432.46 CAS号208255-80-5 纯度98% 溶剂/溶解度Water<1mg/ml; DMSO86mg/ml; Ethanol50mg/ml 溶液配制5mg加入1.16ml DMSO,或者每4.32mg加入1ml DMSO,配制成10mM溶液。SF4139-10mM用DMSO配...
关键字 Gamma secretase | Amyloid-β | DAPT | Inhibitor | Autophagy | LY374973 | Apoptosis | Abeta | LY 374973 | Notch | γ-secretase | inhibit | β-amyloid peptide 相关产品 Guanidine hydrochloride | Naringin | Valproic Acid | L-Glutamic acid | Gefitinib | Hydroxychloroquine | Dextran sulfat...
别名DAPT (GSI-IX), Gamma-Secretase Inhibitor IX, CHEBI:86193, MFCD04974585 中文名N/A 化学式C23H26F2N2O4 分子量432.46 CAS号208255-80-5 纯度98% 溶剂/溶解度Water<1mg/ml; DMSO86mg/ml; Ethanol50mg/ml 溶液配制5mg加入1.16ml DMSO,或者每4.32mg加入1ml DMSO,配制成10mM溶液。SF4139-10mM用DMSO配...
别名DAPT (GSI-IX), Gamma-Secretase Inhibitor IX, CHEBI:86193, MFCD04974585 中文名N/A 化学式C23H26F2N2O4 分子量432.46 CAS号208255-80-5 纯度98% 溶剂/溶解度Water<1mg/ml; DMSO86mg/ml; Ethanol50mg/ml 溶液配制5mg加入1.16ml DMSO,或者每4.32mg加入1ml DMSO,配制成10mM溶液。SF4139-10mM用DMSO配...
别名DAPT (GSI-IX), Gamma-Secretase Inhibitor IX, CHEBI:86193, MFCD04974585 中文名N/A 化学式C23H26F2N2O4 分子量432.46 CAS号208255-80-5 纯度98% 溶剂/溶解度Water<1mg/ml; DMSO86mg/ml; Ethanol50mg/ml 溶液配制5mg加入1.16ml DMSO,或者每4.32mg加入1ml DMSO,配制成10mM溶液。SF4139-10mM用DMSO配...
gamma-secretase inhibitor, DAPT inhibits self-renewal and stemness maintenance of ovarian cancer stem- like cells in vitro. Chin J Cancer Res 2011;23:140-6.Jiang LY,Zhang XL,Du P. γ-Secretase Inhibitor,DAPT Inhibits Self-renewal and Stemness Maintenance of Ovarian Cancer Stem-like Cells In...
1. Lanz TA, et al. The gamma-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester reduces A beta levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice.(2003) J Pharmacol Exp Ther. 305(3)...
SF4139-25mg DAPT (γ-secretase抑制剂) 25mg 1132.00元 化学信息: 化学名 tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate 简称 DAPT 别名 DAPT (GSI-IX), Gamma-Secretase Inhibitor IX, CHEBI:86193, MFCD04974585 中文名 N/A 化学式...
DAPT 是一种γ-分泌酶抑制剂。 在体外抑制 Notch 信号传导。 抑制人类原代培养物中总 Aβ 和 Aβ42 的产生(IC50 值分别为 115 和 200 nM),对 APPα 和 APPβ 水平没有影响。 可透过血脑屏障。 3D 生长基质成分和脑类器官分化介质的成分。图1.DAPT化学结构DAPT基础信息产品名:DAPT;γ-分泌酶抑制剂;γ...