Glucuronyl C5 epimerase is a key enzyme in the biosynthesis of heparin and heparan sulfate (HS), which are complex sulfated glycosaminoglycans ( GAGs ) composed of alternating hexuronic acid and glucosamine residues. Both species are synthesized as proteoglycans but on different core proteins ( Esko...
Kiev, Ukraine; 4Engelhard Institute of Molecular Biology RAS, Moscow, Russia BACKGROUND: D-Glucuronyl C5-epimerase (GLCE) is a key enzyme involved in the biosynthesis of heparan sulphate proteoglycans, which has an important role in cell – cell and cell – matrix interactions and signalling. ...
Rabbit anti-human D-glucuronyl C5-epimerasel polyclonal Antibody 供应商 MyBioSource 产品货号 MBS1488634 产品报价 ￥询价/0.05mg ￥询价/0.1mg ￥询价/其它规格 产品说明书 点击查看 购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系...
货号:QIY-09339 非神经元性烯化酶(ENO1)ELISA测试盒 英文名称:Chemokine C-C-Motif Ligand 3 Like Protein 1 (CCL3L1)ELISA Kit 试剂盒别称:HSEPI; D-Glucuronyl C5-Epimerase; UDP-Glucuronic Acid Epimerase; Heparan Sulfate Epimerase; Heparin/heparan sulfate:glucuronic acid C5-epimerase 规格:48人份/96...
Heparansulfate proteoglycans (HSPG) play an important role in cell–cell and cell–matrix interactions and signaling, and one of the key enzymes in heparansulfate biosynthesis is d-glucuronyl C5-epimerase (GLCE). A tumor suppressor function has been demonstrated for GLCE in breast and lung carcin...
然而,肝内脂代谢的调节机制与肝因子表达分泌调控尚未完全阐明。 葡萄糖醛酸C5异构酶 (Glucuronyl C5-epimerase,Glce) 作为细胞膜上广泛存在的硫酸乙酰肝素蛋白聚糖 (HSPG) 糖链合成修饰的重要异构化酶,其基因高度保守,但其是否参与肥胖症的发生发展以及其调控机制尚不清楚。
Heterogeneity of D-glucuronyl C5-epimerase expression and epigenetic regulation in prostate cancer. Cancer Medicine 2013; doi:10.1002/cam4.108Prudnikova TY, Soulitzis N, Kutsenko OS, Mostovich LA, Haraldson K, Ern- berg I, et al. Heterogeneity of d-glucuronyl C5-epimerase expression and ...
Decreased expression of human D-glucuronyl C5-epimerase in breast cancer. Int J Cancer 2008; 122:1172-6; PMID:17985344; http://dx.doi.org/10.1002/ijc.23203.Grigorieva E, Eshchenko T, Rykova VI, Chernakov A, Zabarovsky ER, Sidorov SV: Decreased expression of human D-glycuronyl C5-...
The TCF4/尾-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer. Epigenetics 2012 ; 7:930 - 9; http://dx.doi.org/ 10.4161/epi.21199 ; PMID: 22805760 [Taylor & Francis Online]...
2012. miRNA-218 contributes to the regulation of D-glucuronyl C5-epimerase expression in normal and tumor breast tissues. Epigenetics 7:1109-1114.Prudnikova, T. Y. et al. miRNA-218 contributes to the regulation of D-glucuronyl C5-epimerase expression in normal and tumor breast tissues. ...